Stereoselective synthesis of two potential metabolites of cis -metconazole

Synthetic approach to iodosulfuron-methyl and metsulfuron-methyl metabolites and their application for water analysis

“…One of our research interests was the development of synthetic methods that can be applied to the synthesis of agrochemicals' process impurities and metabolites. 24 The properties of these compounds have to be extensively surveyed to fully assess the safety of active substances. 25 Prompted by the commercial demand and recognizing that derivatives 3–13 are of limited availability, we decided to develop synthetic routes to these compounds.…”

A synergistic combination of SDS and TX-100 for the catalytic oxidation of an aromatic alcohol in aqueous media

“…The product, 4chlorobenzaldehyde, is an important intermediate produced in pharmaceutical industry mainly. [37][38][39] The functions of two promoters Bpy and Phen on the oxidation kinetic has been scrutinized in microheterogeneous media. The signi cant growth of reaction rate was observed when Bpy participated in oxidation mechanism and nanomicellar media (SDS and SDS/TX-100) accommodate the reactant species fructuously during the course of reaction.…”

Electrosynthesis of 1,2,4-Triazolium Tetrafluoroborates

“…Electrochemical methods are of high interest in metabolic studies as they mimic enzymatic processes and therefore allow for identification and isolation of potential metabolites . In the course of our research toward syntheses of bioactive compounds metabolites, we investigated anodic oxidation of (±)-triticonazole ( 1 ), a widely used agrochemical fungicide. We envisioned that the CC bond oxidation followed by trapping of the radical cation by 1,2,4-triazole structural motif could provide access to novel 1,2,4-triazolium salts (Scheme C), plausible intermediates in metabolism of 1 .…”