Stereotactic 11-Gauge Vacuum-Assisted Breast Biopsy: A Validation  Study

Pfarl, Georg; Helbich, Thomas H.; Riedl, Christopher C.; Wagner, Teresa; Gnant, Michael; Rudas, Margaretha; Liberman, Laura

doi:10.2214/ajr.179.6.1791503

Cited by 134 publications

(73 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We were able to examine the specimens' mammography in all 66 lesions. The mean number of VASB specimens per lesion was 8.4±3.2 (range, [8][9][10][11][12]. It was possible to validate the microcalcifications on all specimen radiograms (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Using this method, 73% of unnecessary surgical excisions could have been avoided in the present study. The false-negative rate for malignancies was reported as 0.6%-3.3%, although this value changes according to the experience of the radiologists (12). The suggested reasons for missed cancers were failure to identify calcium on specimen radiographs, failure to identify calcium at histologic analysis, imaging-histologic discordance, or a combination of these features.…”

Section: Discussionmentioning

confidence: 99%

“…The 11-gauge VASB allows radiologists to obtain a sufficiently large specimen with better calcification retrieval (8), a lower re-biopsy rate, and fewer histologic underestimates (9)(10)(11), compared with other core-needle biopsy techniques. The false-negative rate of VASB procedure can be as low as 0.6% when performed by experienced radiologists (12). This technique also has some cost advantages compared to needle-localized surgical biopsy (NLSB) (13).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Vacuum-assisted stereotactic biopsy for isolated BI-RADS 4 microcalcifications: evaluation with histopathology and midterm follow-up results

Atasoy

Tasalı²,

Çubuk³

et al. 2015

Diagn Interv Radiol

View full text Add to dashboard Cite

ORIGINAL ARTICLE PURPOSE The aim of this study was to evaluate the 10-gauge vacuum-assisted stereotactic biopsy (VASB) of isolated Breast Imaging Reporting and Data System (BI-RADS) 4 microcalcifications, using histology and follow-up results. METHODSFrom January 2011 to June 2013, VASB was performed on 132 lesions, and 66 microcalcification-only lesions of BI-RADS 4 were included into our study. VASB was performed using lateral decubitis stereotaxy for all patients. Pathologic results of VASB and further surgical biopsies were reviewed retrospectively. Patients who were diagnosed to have benign lesions by VASB were referred for follow-up. VASB and surgical histopathology results were compared to determine the underestimation ratios. RESULTSFifteen out of 66 lesions from 63 patients (median age, 47 years; range, 34-88 years) were identified as malignant by VASB. Pathological results after surgery revealed three cases of invasive ductal carcinoma among the 12 VASB-diagnosed ductal carcinoma in situ (DCIS) lesions, for a DCIS underestimation rate of 25%. The atypical ductal hyperplasia underestimation rate was 0% for the three lesions. The follow-up period was at least 10 months, with an average of 22.7 months for all patients and 21.2 months for patients with VASB-diagnosed benign lesions. None of the patients had malignancy during the follow-ups. The false-negative rate was 0% in the follow-up of 48 patients. CONCLUSION VASB should be the standard method of choice for BI-RADS 4 microcalcifications. This method obviates the need for a surgical procedure in 73% of BI-RADS 4 microcalcification-only patients.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Vacuum-assisted stereotactic biopsy for isolated BI-RADS 4 microcalcifications: evaluation with histopathology and midterm follow-up results

Atasoy

Tasalı²,

Çubuk³

et al. 2015

Diagn Interv Radiol

View full text Add to dashboard Cite

show abstract

“…At pathology, lesions were grouped into malignant (in situ, invasive, and metastatic cancer), atypical ductal hyperplasia (ADH), and benign lesions (all other histopathologic findings; ref. 26). ADH was defined as proliferative epithelial lesions that possessed some, but not all, of the features of DCIS (27).…”

Section: Methodsmentioning

confidence: 99%

Magnetic Resonance Imaging of the Breast Improves Detection of Invasive Cancer, Preinvasive Cancer, and Premalignant Lesions during Surveillance of Women at High Risk for Breast Cancer

Riedl

Ponhold²,

Flöry³

et al. 2007

Clinical Cancer Research

Self Cite

View full text Add to dashboard Cite

Purpose: To assess the diagnostic accuracy of mammography, ultrasound, and magnetic resonance imaging (MRI) of the breast in the surveillance of women at high risk for breast cancer. Experimental Design: In this prospective comparison study, women at high risk for breast cancer were offered annual surveillance examinations, consisting of mammography, ultrasound, and MRI, at a single tertiary care breast center.The sensitivity and specificity of each modality was based on the histopathologic evaluation of suspicious findings from all modalities plus the detected interval cancers. Results: Three hundred and twenty-seven women underwent 672 complete imaging rounds. Of a total of 28 detected cancers, 14 were detected by mammography, 12 by ultrasound, and 24 by MRI, which resulted in sensitivities of 50 %, 42.9 %, and 85.7 %, respectively (P < 0.01).MRI detected not only significantly more invasive but also significantly more preinvasive cancers (ductal carcinoma in situ). Mammography, ultrasound, and MRI led to 25, 26, and 101 falsepositive findings, which resulted in specificities of 98%, 98%, and 92%, respectively (P < 0.05).Thirty-five (35%) of these false-positive findings were atypical ductal hyperplasias, lesions considered to be of premalignant character. Nine (26%) of those were detected by mammography, 2 (6%) with ultrasound, and 32 (91%) with MRI (P < 0.01). Conclusion:Our results show that MRI of the breast improves the detection of invasive cancers, preinvasive cancers, and premalignant lesions in a high-risk population and should therefore become an integral part of breast cancer surveillance in these patients.

show abstract

“…Cincinnati, OH, USA), a relatively non-invasive and safe procedure, has become popular in the last decade. 9,10 There is still no consensus on the optimal treatment for GLM, although wide excision of the breast mass seems to be the procedure of choice.…”

Section: Introductionmentioning

confidence: 99%

Vacuum-assisted biopsy and steroid therapy for granulomatous lobular mastitis: Report of three cases

et al. 2009

View full text Add to dashboard Cite

show abstract

Stereotactic 11-Gauge Vacuum-Assisted Breast Biopsy: A Validation Study

Abstract: Stereotactic 11-gauge vacuum-assisted biopsy had a false-negative rate of 3.3% that diminished to 0.6% with experience. All false-negative findings could be prospectively identified because of failure to sample calcifications or imaging-histologic discordance.

Cited by 134 publications

References 24 publications

Vacuum-assisted stereotactic biopsy for isolated BI-RADS 4 microcalcifications: evaluation with histopathology and midterm follow-up results

Vacuum-assisted stereotactic biopsy for isolated BI-RADS 4 microcalcifications: evaluation with histopathology and midterm follow-up results

Magnetic Resonance Imaging of the Breast Improves Detection of Invasive Cancer, Preinvasive Cancer, and Premalignant Lesions during Surveillance of Women at High Risk for Breast Cancer

Vacuum-assisted biopsy and steroid therapy for granulomatous lobular mastitis: Report of three cases

Contact Info

Product

Resources

About