Stereotactic ablative radiotherapy for oligometastatic breast cancer in elderly patients

Abstract

Breast cancer (BC) is the principal cause of cancer-related death in women. Metastatic patients are usually treated with a systemic therapy, but clinical results are limited. Oligometastatic subjects can benefit from high-precision radiotherapy techniques to potentially achieve a complete response. Currently, there is limited evidence of stereotactic ablative radiotherapy (SABR) treatments in elderly oligometastatic cancer patients. A review of the medical literature was performed in PubMed database to assess the current role of SABR in the treatment of breast oligometastases in elderly patients. SABR represents a feasible and safe therapeutic approach in oligometastatic elderly BC patients. Further studies are required to establish the optimum patient selection and treatment scheme.

Older breast cancer patients: challenges facing oncologists

“…A short course of radiotherapy may be ideal for older breast cancer patients because of reduced cost while minimizing the inconvenience associated with daily transportation ( 6 ). Excellent loco-regional control is reported by different institutions across the world in this special topic and in cases of oligometastases, the chance for improving the patient quality of life ( 7 ). Thus, each patient case should be discussed by a team of trained specialists familiar with the management of older cancer patients such as surgical, medical, radiation oncologists, and geriatricians.…”