Stereotactic Radiosurgery and Radiotherapy in the Management of High-Grade Gliomas

Roberge, David; Souhami, Luís

doi:10.1007/978-1-4614-8363-2_17

Principles and Practice of Stereotactic Radiosurgery 2015

DOI: 10.1007/978-1-4614-8363-2_17

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Stereotactic Radiosurgery and Radiotherapy in the Management of High-Grade Gliomas

David Roberge

Luís Souhami

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2020

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Cited by 1 publication

References 102 publications

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Modern Treatments for Gliomas Improve Outcome

Giambattista

Omene

Souied

et al. 2020

CCTR

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: Glioma is the most common type of tumor in the central nervous system (CNS). Diagnosis is made by history, physical examination, radiology, histology and molecular profiles. Magnetic resonance imaging is a standard workup for all CNS tumors. Multidisciplinary team management is strongly recommended. The management of low grade gliomas is still controversial with regards to early surgery, radiotherapy, chemotherapy, versus watchful waiting. Patients with suspected high grade gliomas should undergo assessment by neurosurgeons for consideration of maximum safe resection to achieve optimal tumor debulking, and to provide adequate tissue for histologic and molecular diagnosis. Post-operative radiotherapy and/or chemotherapy are given depending on disease grade and patient performance. Most consider glioblastoma incurable. Treatment approaches in the elderly, pediatric population and recurrent gliomas are discussed with latest updates in the literature. Treatment considerations include performance status, neurocognitive functioning, and co-morbidities. Important genetic mutations, clinical trials and guidelines are summarized in this review.

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Modern Treatments for Gliomas Improve Outcome

Giambattista

Omene

Souied

et al. 2020

CCTR

View full text Add to dashboard Cite

show abstract

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Stereotactic Radiosurgery and Radiotherapy in the Management of High-Grade Gliomas

Cited by 1 publication

References 102 publications

Modern Treatments for Gliomas Improve Outcome

Modern Treatments for Gliomas Improve Outcome

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