“…In fact, of the studies in our analysis in which a normal IGF-I level was the only criterion for hor-monal cure, the rates of endocrinological remission ranged from 20% to 71%. 18,20,36,48,60 As hormonal remission rates following radiosurgery were noted in 17% to 82% of patients in studies in which the more stringent criteria were applied, 2,4,5,14,16,21,33,[45][46][47]53,54,57,58 it appears that the definition of endocrinological remission is of variable consequence.…”