Stereotactic Radiotherapy in Nasopharyngeal Carcinoma

Fractionated stereotactic radiotherapy in residual or recurrent nasopharyngeal carcinoma

“…At our hospital the linac-based radiosurgery system was installed in 1997 and we started treating nasopharyngeal cancer cases in 1998. Our preliminary results [19] showed that the crude local control rate was much different in the boost group (controlled 8/8 cases, follow-up time 2 Á33 months) compared to the retreatment group (controlled 6/11 cases, follow-up time 4 Á19 months). This study was conducted to explore the results from longer follow-up of the retreatment group.…”

Fatal Intratumoral Hemorrhage Immediately after Gamma Knife Radiosurgery for Brain Metastases: Case Report

“…Risk factors for clinically significant acute adverse reactions include large size of the lesion, its location in a critical brain area, prominent peritumoral edema, intracranial hypertension, and high irradiation dose 2 3 5 6 . Nevertheless, the symptoms are usually mild-to-moderate and at the time of deterioration only few patients need re-admission to hospital 3 4 5 6 . Periprocedural administration of dexamethasone (16 mg/day for 2 days) is considered as an effective prophylactic measure 1 2 .…”

“…Radiosurgery, particularly gamma knife radiosurgery (GKR), is a highly effective management option for both single and multiple metastatic brain tumors. Acute adverse reactions after treatment are not uncommon, but are usually transient and generally are well controlled by medication 1 2 3 4 5 6 . Hemorrhage into intracranial tumor after radiosurgery is extremely rare, but can potentially lead to catastrophic consequences due to acute compression of the eloquent brain structures 7 8 .…”