Stereotactic vacuum-assisted breast biopsies in 500 women with microcalcifications: radiological and pathological correlations

Minimizing underestimation rate of microcalcifications excised via vacuum-assisted breast biopsy: a blind study

“…This has led to the taking of 24-36 cores in the common clinical practice. Noticeably, the exact number of offsets used is not definite in the majority of studies, and the mean number of cores excised does not exceed 23 cores [11][12][13][14][15][16][23][24][25][26][27].…”

“…In addition to the above, VABB can be easily performed in the outpatient setting, which has led to it becoming an integral part of the work-up of patients with suspicious breast lesions [10,11]. More specifically, the method has been proven very useful for the biopsy of microcalcifications [12,13].…”

Vacuum-assisted biopsy diagnosis of atypical ductal hyperplasia and patient management

“…Considered a potential precursor to invasive cancer, ADH requires accurate and early detection to best defi ne its prognostic significance. With the recent World Health Organisation (WHO) 2003 pathological classifi cation, Tavassoli introduced the term "ductal intraepithelial neoplasia" (DIN) to cover the possible changes that lead from epithelial hyperplasia to invasive carcinoma, in agreement with the commonly accepted progression model of breast cancer whereby ADH, ductal carcinoma in situ (DCIS) and infi ltrating Le lesioni erano state preliminarmente valutate, relativamente al grado sospetto, in accordo con la classifi cazione breast imaging reporting and data system (BI-RADS) [5,6]. In tutti i casi per la microbiopsia percutanea era stato utilizzato un tavolo prono stereotassico digitale Fischer associato a sistema Mammotome (Ethicon Endo-Surgery, Breast care, Norstedlt, Germania), che permette la campionatura multidirezionale (360°) della lesione con aspirazione forzata (23)(24)(25).…”

Real-time US elastography in the differentiation of suspicious microcalcifications on mammography

“…However, as the specificity of mammography for the differentiation of benign and malignant microcalcifications remains low, ranging from 10-60% [2], approximately 67-78% of percutaneous or surgical biopsies have ultimately proven the microcalcifications to be benign [3][4][5][6]. The role of ultrasound (US) for the evaluation of microcalcifications detected at mammography remains controversial, although several studies have shown that microcalcifications can be identified by US in 23-93% of cases and can be sampled by US guidance with a 78-100% success rate [7][8][9].…”