Steriods of the spirostan and furostan series from plants of the genus Allium

Haemolytic Activity and Immunological Adjuvant Effect of a New Steroidal Saponin from Allium ampeloprasum var. porrum

“…-Plants of the genus Allium are known for their production of steroidal saponins, as well as organosulfur compounds [1] [2]. Steroidal saponins have a wide spectrum of biological properties, including antifungal, antibacterial, cytotoxic, haemolytic, hypocholesteremic, anti-inflammatory, and immunomodulatory activities [3].…”

Allium ampeloprasum

“…Steroid glycosides found in leek included: aginoside, a diosgenin glycoside C 39 H 64 O 15 , ampeloside B S1 , ampelosideB f1 and ampeloside B f2 (Kravets et al 1990 ). Four sapogenins, porrigenins A and B, identifi ed as (25 R )-5α-spirostan-2β,3β,6β-triol and (25 R )-2-oxo-5α-spirostan-3β,6β-diol, respectively, and neoporrigenins A and B were also isolated from Allium porrum (Carotenuto et al 1997b ).…”

Allium sativum

“…An azurogen C steroid glycoside C 57 H 96 O 30 was isolated from garlic (Kravets et al 1990 ). A furostanol glycoside was isolated from garlic bulb and its structure elucidated as 26-O -β-glucopyranosyl 22-hydroxy-25(R)-5α-furostane-3β, 6β, 26-triol 3-O -β-glucopyranosyl(1→2)-[β-glucopyranosyl(1→3)]-β-glucopyranosyl-(1→4)-β-galactopyranoside, i.e.…”