Steroid cell tumor

Das, Ananya; Panda, Sasmita; Singh, Ahanthem Santa

doi:10.4103/0973-1482.144364

Cited by 10 publications

(6 citation statements)

References 4 publications

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“…The majority of these tumors have benign behavior or like low-grade tumors. However, clinically malignant behavior occurs in 25-40% of the patients usually within the peritoneal cavity and rarely at distant sites [6,10]. Most of these cases are unilateral tumors, only 6% of the cases are found to be bilateral [4].…”

Section: Discussionmentioning

confidence: 99%

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Ovarian Steroid Cell Tumor (Not Otherwise Specified): A Case Report of Ovarian Hyperandrogenism

Hadjkacem

Ghorbel

Safi

et al. 2020

Case Reports in Oncological Medicine

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Steroid cell tumors (SCTs) (not otherwise specified (NOS)) are rare sex cord-stromal tumors of the ovary. These are associated with hormonal disturbances resulting in menstrual bleeding patterns and androgenic effects. We report the case of a 36-year-old female presented with hirsutism, signs of virilization, and elevated androgen levels. Transvaginal ultrasound showed a solid-appearing right ovarian mass. She underwent fertility-sparing surgery with a laparoscopic left oophorectomy. Histological examination showed a benign steroid cell tumor, NOS. These tumors often small can then present a problem of positive diagnosis responsible for a delay in the diagnosis.

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Section: Discussionmentioning

confidence: 99%

“…Chemotherapy may be applied using the BEP regimen (bleomycin (20 U/m 2 every 3 weeks for 4 cycles), etoposide (75 mg/m 2 on days 1-5, every 3 weeks for 4 cycles), and cisplatin (20 mg/m 2 on days 1-5, every 3 weeks for 4 cycles)) or other medications [7]. To date, very few reports have investigated the efficacy of radiation or chemotherapy for SCTs [10].…”

mentioning

confidence: 99%

Ovarian Steroid Cell Tumor (Not Otherwise Specified): A Case Report of Ovarian Hyperandrogenism

Hadjkacem

Ghorbel

Safi

et al. 2020

Case Reports in Oncological Medicine

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“…SCT-NOS tends to affect young women, with a mean age of 43 years and occasionally before puberty [ 3 ]. Most are benign, but 25–40% tend to have malignant activity, such as peritoneal metastasis, and they tend to be unilateral [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Rare virilizing tumor: ovarian steroid cell tumor, not otherwise specified: a case report

2022

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Background Ovarian steroid cell tumors, not otherwise specified is a rare sex cord-stromal tumor. Almost 60% of all steroid cell tumors are categorized as not otherwise specified and represent less than 0.1% of all ovarian neoplasm. Some of them are endocrinologically active, producing virilization signs in young women. The recommended treatment is primarily surgical. Case presentation We present the case of a 20-year-old Mexican woman with secondary amenorrhea and virilization signs. She was treated with combined oral contraceptives from 13 years old, due to a misdiagnosis of polycystic ovarian syndrome. However, 4 months after stopping medication, amenorrhea and virilization signs worsened. Biochemically, she had high serum total testosterone and free testosterone levels, and a pelvic and transvaginal ultrasound followed by a pelvic tomography scan demonstrated a right adnexal tumor. She underwent right salpingo-oophorectomy and the histopathological and immunochemistry exams confirmed the diagnosis. The patient was followed for a year after surgery and until then, her menses were regular and she had no recurrence of virilization signs. Conclusion The purpose of this case report is to alert physicians to rule out ovarian steroid cell tumor, not otherwise specified diagnosis in young women with increased testosterone after discarding common causes such as polycystic ovarian syndrome. A multidisciplinary team including a gynecologist, endocrinologist, radiologist, and pathologist should be involved for correct diagnosis at the proper time.

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“…To date, very few reports have investigated the efficacy of radiation or chemotherapy for SCTs (13). However, malignant SCT-NOS should be managed with total abdominal hysterectomy, bilateral salpingo-oophorectomy and sampling of pelvic and mesenteric lymph nodes and omentum followed by combination chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

Ovarian steroid cell tumor, not otherwise specified: A case report and literature review

Qian

Shen

Xue-fen

et al. 2016

Molecular and Clinical Oncology

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Abstract. Steroid cell tumors (SCT), not otherwise specified (NOS) are particularly rare ovarian sex cord-stromal tumors, which comprise <0.1% of all ovarian tumors. These tumors are uncommon in patients' prior to puberty without any typical syndromes involving hirsutism, virilization and hypertension. We here in present the case of a 5-year-old female patient who presented with sudden abdominal pain, repeated vomiting and a pelvic mass. Our patient underwent urgent exploratory laparotomy and right salpingo-oophorectomy and the histopathological examination revealed an ovarian SCT-NOS. The patient has been followed up for 5 years since the surgery, without evidence of disease recurrence. The purpose of this study was to discuss the available information on the presentation, diagnosis and recommended treatment of ovarian SCT-NOS; and describes the immunohistochemical characteristics of these tumors.

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Steroid cell tumor

Cited by 10 publications

References 4 publications

Ovarian Steroid Cell Tumor (Not Otherwise Specified): A Case Report of Ovarian Hyperandrogenism

Ovarian Steroid Cell Tumor (Not Otherwise Specified): A Case Report of Ovarian Hyperandrogenism

Rare virilizing tumor: ovarian steroid cell tumor, not otherwise specified: a case report

Ovarian steroid cell tumor, not otherwise specified: A case report and literature review

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