2005
DOI: 10.1038/sj.bdj.4812929
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Steroid-induced psychosis complicating orthognathic surgery: A case report

Abstract: Psychosis is an uncommon but well-recognised complication of short-term corticosteroid administration. We report a case of steroid-induced psychosis subsequent to a bimaxillary osteotomy.

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Cited by 22 publications
(14 citation statements)
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“…Fisher [7,8] described two cases of visual hallucinations on eye closure attributed to atropine toxicity and lidocaine as the local anesthetic for minor surgery. In our patient, hydrocortisone, fentanyl, ephedrine, and midazolam, along with atropine and lidocaine could be candidate hallucinogens [9][10][11][12], although the doses were not excessive. Microembolic insult to the pulmonary circulation resulting in cerebral hypoxic damage and/or direct damage to the visual association cortex may cause visual hallucinations on eye closure [3].…”
Section: Discussionmentioning
confidence: 77%
“…Fisher [7,8] described two cases of visual hallucinations on eye closure attributed to atropine toxicity and lidocaine as the local anesthetic for minor surgery. In our patient, hydrocortisone, fentanyl, ephedrine, and midazolam, along with atropine and lidocaine could be candidate hallucinogens [9][10][11][12], although the doses were not excessive. Microembolic insult to the pulmonary circulation resulting in cerebral hypoxic damage and/or direct damage to the visual association cortex may cause visual hallucinations on eye closure [3].…”
Section: Discussionmentioning
confidence: 77%
“…[4][5][6][7][8][9][10] In reconstructive head and neck cancer surgery, GCs also are believed to lower the risk of complications, such as prolonged intubation and sedation, and prevent edema in the area of the anastomosis and possible flap loss, thus improving patient recovery. However, even short-term (<1-week) GC use can cause severe complications, [11][12][13][14] wound-healing problems, and postoperative infections. [15][16][17] In their previous study, the authors reported that major complications occurred more frequently in patients administered GCs than in the control group (P = .012).…”
Section: Q3mentioning
confidence: 99%
“…Corticosteroid treatments have been well documented to cause severe emotional and even psychiatric disturbances, ranging from mood disturbances to (florid) psychosis [7,12,19,31]. Typical sequelae from the use of corticosteroids can include symptoms such as insomnia, euphoric moods, mood disorders (with depressive, manic and mixed features), mania and visual hallucinations [12,14,25,27], severe depression [13], irritability, violence [1], neuropsychological deficits and psychotic states [15,25,32].…”
Section: Introductionmentioning
confidence: 99%