Steroid pulse therapies in dermatology

Gupta, Gourav; Jain, Ambuj; Narayanasetty, Naveen Kikkeri

doi:10.4103/0975-9727.135756

Cited by 6 publications

(2 citation statements)

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“…Other GCS side effects occur also less frequently after IV compared to oral route, which may be a result of the specific action of high GCS doses [12]. Buttgereit et al postulated three "modules" of glucocorticoid effect on cells resulting from different concentrations: i) low concentrations mediate effects via genomic events, ii) medium concentrations bind to cell surface receptors, which activate cross membrane signal transmission for genomic and non-genomic intracellular events, and iii) at very large concentrations steroids dissolve in the cell membrane resulting in greater membrane stability and reduced non-genomic cell function [13,14].…”

Section: Discussionmentioning

confidence: 99%

The influence of Graves’ orbitopathy treatment with intravenous glucocorticoids on adrenal function

Ambroziak

Bluszcz

Bednarczuk

et al. 2017

Endokrynologia Polska

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Section: Discussionmentioning

confidence: 99%

The influence of Graves’ orbitopathy treatment with intravenous glucocorticoids on adrenal function

Ambroziak

Bluszcz

Bednarczuk

et al. 2017

Endokrynologia Polska

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“…Another way is by dissolving systemic corticosteroid in 150-200 ml of 5% dextrose and slowly infusing it intravenously for 2-3 hours. [24][25][26] The study conducted by…”

Section: Intravenous Pulse Dose Therapymentioning

confidence: 99%

Pulse Dose Corticosteroid Therapy in Vitiligo: A Narrative Literature Review

Nurfaiqoh¹,

Kusumawardani²

2022

Bioscmed

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Vitiligo is an idiopathic skin depigmentation disorder with clinical symptoms of macules and depigmented patches on the skin. Vitiligo is a multifactorial disorder associated with genetic and non-genetic. There are two types of vitiligo: non-segmental and segmental vitiligo. The type of vitiligo can be determined based on physical examination and affects the disease course, prognosis, and therapy response. Vitiligo management is still a challenge on its own because the etiology is not clear, and many factors must be considered in the vitiligo treatment. Vitiligo management greatly varies depending on the activity and the disease expansion. The goals of vitiligo treatment include stopping disease progression, increasing repigmentation, and preventing recurrence. Vitiligo therapy options vary widely, but none have been effective in treating vitiligo with a high recurrence rate. One of the vitiligo treatment options is systemic corticosteroids given in pulse doses bringing the effect of decreasing the vitiligo progression and minimizing side effects. This literature review aims to determine the use of pulse dose corticosteroid therapy in vitiligo.

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Systemic Therapy in Paediatric Dermatology

Pozzo‐Magaña

Lara‐Corrales

2019

Harper's Textbook of Pediatric Dermatology

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Steroid pulse therapies in dermatology

Cited by 6 publications

References 1 publication

The influence of Graves’ orbitopathy treatment with intravenous glucocorticoids on adrenal function

The influence of Graves’ orbitopathy treatment with intravenous glucocorticoids on adrenal function

Pulse Dose Corticosteroid Therapy in Vitiligo: A Narrative Literature Review

Systemic Therapy in Paediatric Dermatology

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