Steroidal Compounds from Roots of Cinnamomum camphora

Fan, Fang; Li, Guo-Qun; Zi-jiang, LI; Zhang, Jie; Yuan, Erdong; Wu, Lei; Ma, Guangqiang; Bae, Young-Soo

doi:10.1007/s10600-020-02979-3

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…Compound 5 was also compared with the known compounds 7 β -hydroperoxycholesterol and 7 α -hydroperoxycholesterol in order to define the stereo center C-7 [ 19 ]. In terms of the chiral center C-24 on the side chain, the 1D NMR data were compared with those of (24 R )-campesterol and (24 S )-methylcholesterol [ 23 , 24 ]. Based on the previous literature and NOE correlations, the absolute configuration of 5 was proposed to be 3 S , 7 R , and 24 S .…”

Section: Resultsmentioning

confidence: 99%

New Verticillene Diterpenoids, Eudesmane Sesquiterpenoids, and Hydroperoxysteroids from the Further Chemical Investigation of a Taiwanese Soft Coral Cespitularia sp.

Lin

Chiou

et al. 2023

Molecules

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An investigation of the chemical composition of a Formosan soft coral, Cespitularia sp., led to one new verticillene-type diterpenoid, cespitulactam M (1); one new eudesmane sesquiterpenoid, cespilamide F (2); and three new hydroperoxysteroids (3–5) along with twelve known analogous metabolites (6–17). In addition, one new derivative, cespitulactam M-6,2’-diacetate (1a), was prepared from compound 1. The structures were determined by detailed spectroscopic analyses, particularly HRESIMS and NMR techniques. Moreover, the in vitro cytotoxicity, anti-inflammatory, and antibacterial activity of 1–17 and 1a were evaluated.

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Section: Resultsmentioning

confidence: 99%

New Verticillene Diterpenoids, Eudesmane Sesquiterpenoids, and Hydroperoxysteroids from the Further Chemical Investigation of a Taiwanese Soft Coral Cespitularia sp.

Lin

Chiou

et al. 2023

Molecules

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“…Apart from analgesic, Kafūr has also been reported for many other pharmacological activities might be due to the presence of monoterpenes, phenolic derivatives, flavonoids, lignans, sterols, and terpenoids [34,37,39,40,[43][44][45]46]; which are reported to have antinociceptive/analgesic [49,50], antioxidant [52], antimicrobial [53][54][55][56][57] and wound healing properties [64]. The antibacterial activity was achieved by different mechanisms like partial degradation of the cell membrane, increased membrane permeability, cytoplasm leakage, noticeable distortion, shrinkage of bacterial cells, and membrane protein structural changes [56].…”

Section: Discussionmentioning

confidence: 99%

Kafur (C. Camphora L.)–an Updated Review of Its Ethnopharmacology, Phytochemistry and Pharmacology

Usmani

Jahan²,

SOFIYA³

2022

Int J Pharm Pharm Sci

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The objective of present review was to provide comprehensive information on Cinnamomum camphora L. on its ethnomedicinal uses, phytochemical, and pharmacological activities and provide insights into potential opportunities for future research. A thorough literature search was done to gather all the available updates on Kafūr for its mizāj (temperament), medicinal properties, and traditional uses. Classical Unani books and books on ethnomedicine and ethnobotany in English were referred for literature review. The information on phytochemical and pharmacological activities of C. camphora was collected from PubMed, Science Direct, Google Scholar, and Research Gate using keywords C. camphora, Kafūr, kapur, and camphor. The species name was checked with www. theplantlist. org. The material published in Urdu, Persian, Arabic, and English was included in the review. C. camphora is used as an analgesic and antiseptic in Unani and other traditional systems of medicine for a long. It possesses various bioactive compounds viz. terpenoids, flavonoids, glycosides, coumarins, fatty acids, lignans, alkaloids, etc. Out of all these, camphor is one of the volatile compounds which has many pharmacological activities including anti-nociceptive, anti-oxidant, anti-bacterial, anti-microbial, wound healing, and hepatoprotective.

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Steroidal Compounds from Roots of Cinnamomum camphora

Cited by 2 publications

References 16 publications

New Verticillene Diterpenoids, Eudesmane Sesquiterpenoids, and Hydroperoxysteroids from the Further Chemical Investigation of a Taiwanese Soft Coral Cespitularia sp.

New Verticillene Diterpenoids, Eudesmane Sesquiterpenoids, and Hydroperoxysteroids from the Further Chemical Investigation of a Taiwanese Soft Coral Cespitularia sp.

Kafur (C. Camphora L.)–an Updated Review of Its Ethnopharmacology, Phytochemistry and Pharmacology

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