2017
DOI: 10.1136/jclinpath-2016-204287
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Steroids administered after vacuum-assisted biopsy in the management of idiopathic granulomatous mastitis

Abstract: The aetiology of IGM remains uncertain. The disease has no propensity for the right or left breast. It is a local autoimmune disease, involving humoral and cell-mediated immunity. Hyperprolactinaemia may play a role in some patients. Corticosteroids administered after complete removal of the IGM lesion using the Mammotome biopsy system is an effective treatment option.

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Cited by 25 publications
(28 citation statements)
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“…A wide local excision with steroid use is the most common treatment (Prasad et al, 2017;Deng et al, 2017;Mahmodlou et al, 2017). There is growing evidence that early introduction of immunosuppressive therapy might be useful in reducing the extent of surgery (Oran et al, 2013) Steroids are the most widely used agents in this context (Pandeyet et al, 2014).…”
Section: A Proposal Of a Clinically Based Classification For Idiopathmentioning
confidence: 99%
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“…A wide local excision with steroid use is the most common treatment (Prasad et al, 2017;Deng et al, 2017;Mahmodlou et al, 2017). There is growing evidence that early introduction of immunosuppressive therapy might be useful in reducing the extent of surgery (Oran et al, 2013) Steroids are the most widely used agents in this context (Pandeyet et al, 2014).…”
Section: A Proposal Of a Clinically Based Classification For Idiopathmentioning
confidence: 99%
“…The etiology of IGM is still not clear. The most widely adopted theory considers IGM to be a local autoimmune disease that involves both humoral and cell-mediated immunity and results in non-caseating granulomas (Deng et al, 2017). No specific triggering antigens or infectious agents have been identified.…”
Section: Introductionmentioning
confidence: 99%
“…Nonetheless, surgical excision may be useful in providing accurate diagnosis 10 . After excision, if there is no infection, recurrence, or wound healing impairment, the treatment can be completed 10,11 .…”
Section: Discussionmentioning
confidence: 99%
“…DeHertogh et al 12 were the first to recommend the use of corticosteroids to treat IGM. Steroid treatment can be administered after excision in complicated and resistant cases, or in patients who had only an incisional biopsy and in initially unresectable lesions before surgery 11,13 . Early diagnosis and administration of corticosteroids may prevent repetitive and deforming breast biopsies, as well as long-term recurrence 13 .…”
Section: Discussionmentioning
confidence: 99%
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