Steroids. CXXXIX.¹ New Fluorination Procedures. Part I. The Addition of Br-F and I-F to Cyclohexene and a Variety of Unsaturated Steroids²

In situ Generation and Electrophilic Addition Reactions of the Elements of 'XF'

“…Although quantitative values for the yields could not be obtained, subjective estimates are 10% for the transisomer (10) and 5% for the cis (9). A series of experiments were carried out to optimize the yield; the percentage of benzene in the solvent was varied from 50-100% and an optimum yield was obtained in the range 80-90% benzene.…”

Stereochemical Consequences of Recoil Halogen Atom Substitution IV : Effect of Kinetic Energy Moderator Concentration on the 18F-for-X (X=Br, F) Reactions in Gaseous Diastereomeric 2,3-Bromofluorobutanes

“…In the general method [18,19], addition of bromide ion to trans-and cis-2-butenes was carried out in the presence of a fluoride ion source to yield net BrF addition across the double bond of each alkene. The source of bromide ions was N-bromosuccinimide (0.06 mol) while that of the fluoride ion was HF in pyridine (20 ml).…”

Stereochemical Consequences of Recoil Halogen Atom Substitution

“…The result were net addition of BrF across the double bond of each olefin [30,31]. The bromide ion source was N-bromosuccinimide (0.06 mole) while the fluoride ion was provided by HF (0.06 mole) in pyridine (20 ml).…”