Steroids in the Long-Term Treatment of Asthma

Livingstone, J. L.; Davies, JE

doi:10.1016/s0140-6736(61)90238-0

Cited by 23 publications

(3 citation statements)

References 3 publications

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“…In the literature, the recent report by Livingstone and Davies (1961) seems to bear the closest resemblance to this one in respect of results, duration of treatment, methods of dosage control, low incidence of serious complications, and numbers of patients treated for two years or more. It is notable that Somner et al (1960) in a trial of long term therapy in only fourteen cases, using comparatively high doses, had serious complications in four of them.…”

Section: Discussionmentioning

confidence: 82%

Asthma, Allergy and Steroids

Brown

1961

Int J Clinical Practice

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Section: Discussionmentioning

confidence: 82%

Asthma, Allergy and Steroids

Brown

1961

Int J Clinical Practice

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“…To investigate whether change in treatment might be related to changing mortality the same authors, in collaboration with Professor L. B. Strang, report at page 339 that they sent questionaries to doctors concerned with all (184) deaths certified as due to asthma in the six months from 1 October 1966. One-third of the deaths occurred in patients who had never received corticosteroids before their terminal illness, another third had had corticosteroids discontinued within the year preceding death, while the remainder had continued on corticosteroids.…”

Section: Increasing Deaths From Asthmamentioning

confidence: 99%

Increasing deaths from asthma.

1968

BMJ

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Death from Asthma: Investigation into apparent increase in mortality shows this to be a true bill in England and Wales, particularly in adolescent age group. No comparable increase observed in other countries. Possible connexion with drugs used has been studied but results are not conclusive (,,p. 335 and 339). Leader this page. Complete Heart Block: Transvenous system of permanent artificial pacemaking found safe and reliable, requiring minimal follow-up when patients are instructed in the hazards and treatment of instrument failure (p. 343). Aetiology of Schizophrenia: Possibility of autoimmune origin not supported by this study,

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“…A number of studies have demonstrated the association between the reversibility of obstructive pulmonary function impairments and the number of eosinophil in peripheral blood. [45] Peripheral blood eosinophilia has generally being regarded as an allergic trait. Storage grain workers also sufferfrom different types allergic symptoms induced by grain dust which may cause eosinophilia.…”

Section: Introductionmentioning

confidence: 99%

A study on blood eosinophil level and ventilatory pulmonary function of the workers exposed to storage grain dust

Chattopadhyay¹,

Mahata²,

Kundu³

et al. 2007

Indian J Occup Environ Med

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The workers engaged in storage grain handling are exposed to storage grain dust and suffer from different respiratory symptoms like, cough wheezing, chest tightness, eye and nasal irritations. It has been reported abroad and the present study results noted that the grain handlers have allergic symptoms like redness of eyes, itching, sneezing, skin rash, breathlessness and decrement of pulmonary function test values. According to their nature of job, the workers of storage grain godowns were divided into four categories i.e., load handling worker (LHW), ancillary, quality control and depot administration workers. The pulmonary function tests (PFT) and the differential count of leucocytes were carried out among the workers by standard technique. Decrement of pulmonary function test values was noted with the increment of blood eosinophil level.The PFT results were presented according to the blood eosinophil level. The decrement of mean PFT values were noticed as the blood level of eosinophil gradually increased from, up to -4%, >4-10% and above 10%. The maximum numbers of workers in different job categories are belonged to >4 -10% of eosinophil level. The percentage figure of workers in different departments were LHW 48.38%, (n=45), ancillary 38.88%, (n=7), quality control 54.54% (n=6) and depot administration workers 47.05% (n=16) are belonged to that range. Among the total workers the higher figure was found >4-10% ranges 47.43% (n=74) workers. The allergic manifestations like redness, itchiness and watering of eyes, sneezing, cough, breathless etc. are reported. These workers have blood eosinophil level and low pulmonary function test values. The respiratory impairments among the workers are restrictive, obstructive and combined restrictive and obstructive type.

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Steroids in the Long-Term Treatment of Asthma

Cited by 23 publications

References 3 publications

Asthma, Allergy and Steroids

Asthma, Allergy and Steroids

Increasing deaths from asthma.

A study on blood eosinophil level and ventilatory pulmonary function of the workers exposed to storage grain dust

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