Cochrane Database of Systematic Reviews 2001
DOI: 10.1002/14651858.cd001316
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Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus

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Cited by 50 publications
(43 citation statements)
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“…The majority of reports for SVC are case studies and randomized trials are rare. In addition to treatment strategies to relieve symptoms, chemotherapy, surgical intervention and radiation therapy are commonly adopted methods of treatment; however, the control rate of the disease remains poor (2). According to previous reports, percutaneous placement of an intravascular stent, which offers rapid relief of the symptoms, is the most common intervention, due to its low level of complexity and low mortality rate (3).…”
Section: Discussionmentioning
confidence: 99%
“…The majority of reports for SVC are case studies and randomized trials are rare. In addition to treatment strategies to relieve symptoms, chemotherapy, surgical intervention and radiation therapy are commonly adopted methods of treatment; however, the control rate of the disease remains poor (2). According to previous reports, percutaneous placement of an intravascular stent, which offers rapid relief of the symptoms, is the most common intervention, due to its low level of complexity and low mortality rate (3).…”
Section: Discussionmentioning
confidence: 99%
“…22 The percentage of lung cancer patients eligible for RT includes those with resectable but nonoperable NSCLC in stages I and II, among whom RT has achieved 5-year survival rates of 22% to 37%. [23][24][25] It also includes the much more numerous group of patients with advanced disease (stages IIIa-b) but preserved general health status (performance status 0-1), who receive RT alone or with CT. [26][27][28][29][30][31][32] Finally, RT with palliative intent has proven beneficial in comparison to support measures alone. [33][34][35] Small-cell tumors can also benefit from treatment with local RT and with whole-brain radiation, which has not been considered here.…”
Section: Discussionmentioning
confidence: 99%
“…[518] Although their role in SVCO is inconclusive,[19] Wan and Bezjak[20] have described steroids to be effective in symptomatic patients of SVCS in whom airway edema is suspected to contribute to the symptoms. Steroids are very useful in decreasing the inflammatory response to tumor invasion and also in decreasing the edema around the tumor, especially in cases of lymphoma.…”
Section: Discussionmentioning
confidence: 99%