Sterols. XV.¹ Cortisone and Analogs. Part 1. 16α-Hydroxy and 16α,17α-Epoxy Analogs of Cortisone

Russell Earl Marker and the Beginning of the Steroidal Pharmaceutical Industry

“…Djerassi joined Syntex in 1949 as Associate Director of Chemical Research (1949–1952), then in a variety of senior positions from 1960–1972. In recent years, in large measure to identify and celebrate the achievements of Black scientists, Percy Lavon Julian (1899–1975) has rightfully been identified as a chemist who made major contributions to the commercial manufacture of steroidal drugs in the 1940s into the 1970s [6–14] . Indeed, into the 1970s and beyond, Julian's patented process provided the highest quality commercial‐scale preparation of pre‐vitamin D. His company, Julian Laboratories, also provided the key intermediate in the manufacture of cortisone.…”

“…In recent years, in large measure to identify and celebrate the achievements of Black scientists, Percy Lavon Julian (1899Julian ( -1975 has rightfully been identified as a chemist who made major contributions to the commercial manufacture of steroidal drugs in the 1940s into the 1970s. [6][7][8][9][10][11][12][13][14] Indeed, into the 1970s and beyond, Julian's patented process provided the highest quality commercialscale preparation of pre-vitamin D. His company, Julian Laboratories, also provided the key intermediate in the manufacture of cortisone. Both Djerassi and Julian were members of the National Academy of Sciences.…”