Steven-Johnson Syndrome in Child

Abstract

Steven-Johnson Syndrome and NET (toxic epidermal necrolysis), different expressions of the same condition were named according to the percentage of affected skin: [10% in Steven-Johnson Syndrome and]30% in NET. Small ages may be a target for these rare diseases, in direct relation to drug abuse (antibiotics, NSAIDs, antiepileptics, etc.). Survival depends on the rapid response of the causative agent, the early investigation of the therapy to block Fas-FasL interaction and to reestablish skin integrity (Fas-receptor on the surface of cells involved in apoptosis). Massive skin damage is associated with a severe prognosis, as is the age of the baby.It is necessary to use wise the medication or automedication for a complete and effective prevention of Steven-Johnson Syndrome.