STI in times of PrEP: high prevalence of chlamydia, gonorrhea, and mycoplasma at different anatomic sites in men who have sex with men in Germany

Jansen, Klaus; Steffen, Gyde; Potthoff, Anja; Schuppe, Ann-Kathrin; Beer, Daniel T.; Jessen, Heiko; Scholten, Stefan; Spornraft‐Ragaller, Petra; Bremer, Viviane; Tiemann, Carsten

doi:10.1186/s12879-020-4831-4

Cited by 133 publications

(106 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Regardless of the question, the best STI knowledge was identified among PrEP-users. In our population, this group was exclusively constituted by MSM and, in line with other cohorts, reported a significantly higher number of sexual partners, exposure to chemsex and history of STIs, as well as less frequent condom use [8]. STI awareness in the MSM population has been evaluated in recent studies, although with contradictory results, depending on the study population and the STI being evaluated (consistently better for HIV than for other STIs) [9,10].…”

Section: Discussionsupporting

confidence: 71%

Sexually transmitted infections knowledge in different populations attending a French university hospital: a prospective observational study

et al. 2021

View full text Add to dashboard Cite

We conducted a prospective study about sexually transmitted infections (STIs) knowledge in different populations attending Lyon's University Hospitals in order to estimate awareness on STIs. Pre-exposure prophylaxis (PrEP)-users (PrEP group), persons living with HIV (PLWH group) and persons undergoing free STI screening (screening group) filled an anonymous questionnaire evaluating STI knowledge. A composite STI knowledge score was calculated and was correlated with patients’ characteristics. A total of 756 patients were enrolled in three groups: screening (n = 509), PrEP (n = 103) and PLWH (n = 144). STI transmission knowledge was better for HIV than for other STIs. The median STI knowledge score was significantly higher in PrEP-users than in the screening and PLWH groups. PrEP use and a previous STI diagnosis were independently associated with a higher score. PrEP-users have better STI knowledge than PLWH and persons undergoing free STI screening. Sexual health promotion interventions routinely reserved to PrEP-users in France seem to be effective in raising the awareness of this group for STIs. Continuous efforts are justified for PLWH and the younger layers of the population.

show abstract

Section: Discussionsupporting

confidence: 71%

Sexually transmitted infections knowledge in different populations attending a French university hospital: a prospective observational study

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The prevalence of HIV among MSMs in the present study was 5.36%; among 575 MSMs from the Netherlands, it was 3.5%; 4 among 2303 MSMs from Germany, 50.5% 5 and in Colombia, a study with 336 MSMs from Bucaramanga reported 11% prevalence. 18 Despite the differences in HIV occurrence, all studies report very high prevalence in this population, thus corroborating the need to join efforts to screen MSMs for infection.…”

Section: Discussioncontrasting

confidence: 53%

“…Studies with MSMs have reported prevalence of 3.5% and 50.5%, with risk factors as high number of sexual partners, sex without condoms, drug use and other STIs. [4][5][6] Among sex workers, the prevalence has been 5% -70%, with a high co-infection of syphilis (5%), chlamydia (8%) and gonorrhoea (2%). 7,8 In persons deprived of liberty have been reported prevalence as low as 0.47% or 2-10 times higher than the general population.…”

Section: Introductionmentioning

confidence: 99%

<p>HIV Prevalence and Associated Factors in Key Groups and General Population Treated at a Health Care Institution in Colombia in 2019: A Cross-Sectional Study</p>

Cardona‐Arias¹,

Correa²,

Higuita-Gutiérrez³

2020

HIV

View full text Add to dashboard Cite

Background: Research conducted on the prevalence of HIV/AIDS and its associated factors among key groups in Colombia is scarce. The few available studies show heterogeneity in their results and increasing trends of infection. This study analyses the prevalence of HIV and associated factors in key groups served at a health care institution in Colombia in 2019. Methods: We performed a cross-sectional study with the sample comprised of 5771 subjects from the general population, the LGBTI community, sex workers, people who inject drugs and prisoners. The diagnosis was based on a fourth-generation ELISA. Variables related to sociodemographics, healthcare, sexual risk factors and biological measures of infected subjects were analysed. Prevalence and odds ratios were calculated with 95% confidence intervals, and logistic regression models were performed to identify confounding variables and interactions between independent variables using SPSS 25.0. Results: The prevalence of HIV was 0.27% among the general population, 0.53% among sex workers, 0.66% among the homeless, 2.44% among transgender persons, 2.44% among prisoners, 5.36% among men who have sex with men and 7.92% among injection drug users. The explanatory model showed higher prevalence among men, those with higher education levels, those with no health coverage, those who have sex with people from key groups and those with sexually transmitted infections, with some interactions between the latter variables. Conclusion: A high prevalence of infection was found in the key groups, while the main explanatory factors for high infection rates were identified. The data show that national and global goals related to controlling HIV have not been achieved mainly in groups that are at a higher risk of obtaining and transmitting it and, paradoxically, also that are excluded from the national health coverage.

show abstract

“…A lack of association between condom use and STI increments was found in one Australian cohort, maybe due to other unknown or unmeasured risk behaviours such as an increase in having new sexual partners [ 21 ]. Nevertheless, the relation between having an STI and PrEP use has been controversial: while some studies have found that PrEP use would increase STI incidence [ 22 – 24 ], others show that PrEP would not lead to STI increases or would even lower STI rates, due to frequent testing and close follow-up of sexual health [ 25 ]. This would be consistent with the fact that having STIs and not using condoms consistently in the last 12 months were inclusion criteria for the study, as well as being and indicative criteria in the national guidelines.…”

Section: Discussionmentioning

confidence: 99%

Implementation of pre-exposure prophylaxis programme in Spain. Feasibility of four different delivery models

Iniesta¹,

Coll²,

Barberà

et al. 2021

PLoS ONE

View full text Add to dashboard Cite

Background Pre-exposure prophylaxis (PrEP) is an effective and cost-effective strategy for HIV prevention. Spain carried out an implementation study in order to assess the feasibility of implementing PrEP programmes within its heterogeneous health system. Methods Observational longitudinal study conducted on four different types of health-care setting: a community centre (CC), a sexually transmitted infections clinic (STIC), a hospital-based HIV unit (HBHIVU) and a hospital-based STI unit (HBSTIU). We recruited gay, bisexual and other men who have sex with men (GBSM) and transgender women at risk of HIV infections, gave them PrEP and monitored clinical, behavioural PrEP-related and satisfaction information for 52 weeks. We collected perceptions on PrEP implementation feasibility from health-care professionals participating in the study. Results A total of 321 participants were recruited, with 99.1% being GBMSM. Overall retention was 87.2% and it was highest at the CC (92.6%). Condom use decreased during the study period, while STIs did not increase consistently. The percentage of people who did not miss any doses of PrEP during the previous week remained at over 93%. No HIV seroconversions occurred. We observed overall decreases in GHB (32.5% to 21.8%), cocaine (27.5% to 21.4%), MDMA (25.7% to 14.3%), speed (11.4% to 5.7%) and mephedrone use (10.7% to 5.0%). The overall participant satisfaction with PrEP was 98.6%. Health-care professionals’ perceptions of PrEP feasibility were positive, except for the lack of personnel. Conclusions PrEP implementation is feasible in four types of health-care settings. Local specificities have to be taken into consideration while implementing PrEP.

show abstract

STI in times of PrEP: high prevalence of chlamydia, gonorrhea, and mycoplasma at different anatomic sites in men who have sex with men in Germany

Cited by 133 publications

References 63 publications

Sexually transmitted infections knowledge in different populations attending a French university hospital: a prospective observational study

Sexually transmitted infections knowledge in different populations attending a French university hospital: a prospective observational study

<p>HIV Prevalence and Associated Factors in Key Groups and General Population Treated at a Health Care Institution in Colombia in 2019: A Cross-Sectional Study</p>

Implementation of pre-exposure prophylaxis programme in Spain. Feasibility of four different delivery models

Contact Info

Product

Resources

About