Sticky situations: cyanoacrylate exposures reported to a poison control system

Carstairs, Shaun D.; Koh, Cynthia; Qian, Lily; Qozi, Mariam; Seivard, Grant; Cantrell, F. Lee

doi:10.1080/15563650.2017.1327067

Cited by 5 publications

(3 citation statements)

References 13 publications

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“…To our knowledge, this is the first study comparing various suggested methods. A recent study by Carstairs et al 10 showed that there was a very wide variation of recommended treatments given by poison control centres to callers. Our review also shows a broad range of proposed interventions but no comparisons done to date.…”

Section: Discussionmentioning

confidence: 99%

Inadvertent tissue adhesive tarsorrhaphy of the eyelid: a review and exploratory trial of removal methods of Histoacryl

2020

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ObjectiveThe use of tissue adhesives has become a popular option for closure of wounds in the ED. There have been a growing number of reports of inadvertent tissue adhesive injuries including closure of the eyelids. We aim to identify and compare various removal methods of tissue adhesives described in the literature in an exploratory trial.MethodsA review was first conducted to establish all published methods for the removal of medical-grade tissue adhesives as well as commercial cyanoacrylates. This search was conducted on PubMed, Google Scholar and Google. All articles that reported attempts at removal of cyanoacrylate glues were included. These methods were then tested on a porcine model in an exploratory trial. Incisions were made on pigskin and closed with Histoacryl, a tissue adhesive. Three removal methods were tested—gentle rubbing with test compound after 45 or 90 s, as well as soaking in test compound. Removal methods that were successful underwent repeat testing.ResultsA total of 37 sources were reviewed with 13 different removal methods suggested. Based on the information, we tested 24 different compounds. Soaking of Histoacryl-closed wounds in Polydexa ear/eye drops displayed consistent success in achieving complete separation of incision edges after 2 hours. Several other soapy substances and antibiotic ointments showed potential but were not as consistent.ConclusionIn conclusion, in our trial of removal methods of Histoacryl, soaking in Polydexa antibiotic drops consistently facilitated removal after 2 hours. This approach can be attempted after inadvertent Histoacryl injury.

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Section: Discussionmentioning

confidence: 99%

Inadvertent tissue adhesive tarsorrhaphy of the eyelid: a review and exploratory trial of removal methods of Histoacryl

2020

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“…In the instance of low quality data, the possible risks become more important. While some of these risks are discussed by the authors, they include wound contamination if appropriate wound cleaning does not occur, exothermic reaction potentially leading to burns, irritant effects, poor cosmetic outcome for large or poorly closed wounds, damage to underlying structures for deep wounds on inappropriate application, and inadvertent self-adhesion to unintended objects (Carstairs et al, 2017;Eyth, Echlin, & Jones, 2016;Kelemen, Karagergou, Jones, & Morritt, 2016). A recent 10-year review of cyanoacrylate exposures reported to a single US regional poison control center found 893 reports of accidental and intentional exposures, of which over 26% required management in a healthcare facility.…”

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confidence: 99%

“…A recent 10-year review of cyanoacrylate exposures reported to a single US regional poison control center found 893 reports of accidental and intentional exposures, of which over 26% required management in a healthcare facility. While most of the effects were minor, just under 9% suffered moderate effects from exposure (Carstairs et al, 2017). Commercial cyanoacrylates are not designed for medical use.…”

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confidence: 99%

Stuck on you and other problems with Superglue

Charlton¹,

Singletary²

2018

IJFAE

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We appreciate the opportunity to comment on the letter by Drs. Bhargava and Hassall. As emergency medicine physicians, we recognize that hospital services are often overwhelmed and we welcome the prospect of home care to decompress these resources. However, as physicians we should strive to provide the best possible treatment options for our patients, both the one's we are directly treating and those we are indirectly treating by way of medical guidelines, and we should rely on the best possible evidence to make these

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