Abstract:Ligases enzymes were discovered as a member of the nucleotidyl transferase family. Here in this paper, DNA Ligase is extracted from S. aureus works with the cofactor NAD + to make a phosphodiester bond and reform between the 3'hydroxyl and 5'phosphate DNA end. Staphylococcus aureus-DNA Ligases Enzyme type A (SLE-A) contains two essential domains; NTase and OB-fold domain, which are the most essential domains for the enzyme function. The main aim of the study is to investigate the activity of SLE-A in the prese… Show more
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