Stimuli-responsive electrospun fibers and their applications

Abstract

In this critical review, an overview is given on recent advances in the development and application of stimuliresponsive electrospun nanofibers.Please check this proof carefully. Our staff will not read it in detail after you have returned it. Translation errors between word-processor files and typesetting systems can occur so the whole proof needs to be read. Please pay particular attention to: tabulated material; equations; numerical data; figures and graphics; and references. If you have not already indicated the corresponding author(s) please mark their name(s) with an asterisk. Please e-mail a list of corrections or the PDF with electronic notes attached --do not change the text within the PDF file or send a revised manuscript.Please bear in mind that minor layout improvements, e.g. in line breaking, table widths and graphic placement, are routinely applied to the final version.Please note that, in the typefaces we use, an italic vee looks like this: n, and a Greek nu looks like this: n.We will publish articles on the web as soon as possible after receiving your corrections; no late corrections will be made.Please return your final corrections, where possible within 48 hours of receipt, by e-mail to: chemsocrev@rsc.org Reprints-Electronic (PDF) reprints will be provided free of charge to the corresponding author. Enquiries about purchasing paper reprints should be addressed via: http://www.rsc.org/publishing/journals/guidelines/paperreprints/. Costs for reprints are below: Stimuli-responsive electrospun nanofibers are gaining considerable attention as highly versatile tools which offer great potential in the biomedical field. In this critical review, an overview is given on recent advances made in the development and application of stimuli-responsive fibers. The specific features of these electrospun fibers are highlighted and discussed in view of the properties required for the diverse applications. Furthermore, several novel biomedical applications are discussed and the respective advantages and shortcomings inherent to stimuli-responsive electrospun fibers are addressed (136 references).

Soft Graphene Nanofibers Designed for the Acceleration of Nerve Growth and Development

“…In this case, the cell preferable naturallike 3D nanofi brous architecture has been destroyed completely, which would decrease sharply the multilocus stimulation effect of nanofi bers to cell and block biomolecules transfer between cell and cell on both sides of the GO fi lm in vivo. [ 26 ] Here, in order to locate the GO sheets into nanofi bers in the 3D electrospun nanofi bers fi lm, a strong ultrasonication process was employed to obtain GO sheets in nanoscale (GO nanosheets) with an average size of 0.43 µm (Figure S2b, Supporting Information). In addition, the NH 3 plasma treatment was used to achieve -NR chemical groups modifi ed surface of the electrospun nanofi bers to drive the assembly of the GO nanosheets (Figure 1 a and Figure S3, Supporting Information).…”

Nanostructures and Nanostructured Networks for Smart Drug Delivery

“…Other feasible methods to prepare membranous hydrogel systems, mainly from preformed polymers, involve phase separation, electrospinning, foaming, particle leaching, emulsion freeze drying, and sintering [251,252].…”

Smart Microfluidics: The Role of Stimuli- Responsive Polymers in Microfluidic Devices

“…(Dalton et al, 2002;Jeong et al, 2004) Cylindrical polymeric structures composed of smart polymers can be employed for the encapsulation and detection of biomolecules.(C. Huang et al, 2011) Different kinds of smart fibers can be obtained, depending on the responsive polymers used. Jeong et al fabricated fibers by employing 3-D multiple stream laminar flow and ''on the fly'' photopolymerization.…”