Stimuli–responsive networks grafted onto polypropylene for the sustained delivery of NSAIDs

Oxaprozin-Loaded Lipid Nanoparticles towards Overcoming NSAIDs Side-Effects

“…They concluded that this grafts cold be used in the design of products for biomedical devices in order to promote a controlled NSAIDs release [53].…”

Biomedical Devices Based on Smart Polymers

“…The dimensions and the surface properties of the medical device and the release of leachable substances determine the intensity and duration of infl ammation and the healing process [104]. Polymeric medical devices occupy a prominent position in current medical care and play a very important role in common diagnostic, therapeutic procedures, and in the management of critically ill patients [105]. However, morbidity and mortality associated with device-related infections have become a relevant source of sanitary and economic worries [106,107].…”

Nanostructures and Nanostructured Networks for Smart Drug Delivery

“…Polypropylene surfaces bearing grafted networks of NIPAAm and N-(3-aminopropyl) methacrylamide hydrochloride (APMA) have been shown to host/elute nalidixic acid to prevent the growth of Escherichia coli [286] and nonsteroidal anti-inflammatory drugs (NSAIDs) to avoid eliciting inflammatory reactions [287]. Furthermore, such a surface modification resulted in improved blood and cell compatibility and decreased the friction coefficient [286,287].…”

“…Furthermore, such a surface modification resulted in improved blood and cell compatibility and decreased the friction coefficient [286,287].…”