STING Report: convenient web-based application for graphic and tabular presentations of protein sequence, structure and function descriptors from the STING database

Abstract

The Sting Report is a versatile web-based application for extraction and presentation of detailed information about any individual amino acid of a protein structure stored in the STING Database. The extracted information is presented as a series of GIF images and tables, containing the values of up to 125 sequence/structure/ function descriptors/parameters. The GIF images are generated by the Gold STING modules. The HTML page resulting from the STING Report query can be printed and, most importantly, it can be composed and visualized on a computer platform with an elementary configuration. Using the STING Report, a user can generate a collection of customized reports for amino acids of specific interest. Such a collection comes as an ideal match for a demand for the rapid and detailed consultation and documentation of data about structure/function. The inclusion of information generated with STING Report in a research report or even a textbook, allows for the increased density of its contents. STING Report is freely accessible within the Gold STING Suite at

Flexible mapping of homology onto structure with Homolmapper

“…However, schemes such as identity or similarity matrices can instead use a consensus sequence or a different sequence found in the alignment as the reference sequence. Consensus sequences can be supplied as part of the input MSA, permitting import of consensus sequences from sources such as HSSP or STING [9,12,33,34], or they can be generated by homolmapper at runtime as needed. A summary of the available reference sequence choices for different scoring schemes is presented in Table 2.…”

Identification of New Sphingomyelinases D in Pathogenic Fungi and Other Pathogenic Organisms

“…The identification of contacts for the SMase D (PDB code “1xx1.pdb”) was obtained using the STING Java Protein Dossier and Sting Report [23,24,27] and its STING Contacts module [28]. Protein structure images were created using the PyMOL Molecular Graphics System, Version 1.5.0.4 Schrödinger, LLC.…”

Induction of Neutralizing Antibodies against Mutalysin-II from Lachesis muta muta Snake Venom Elicited by a Conformational B-cell Epitope Predicted by Blue Star Sting Data Base

“…Prediction of the epitopes by selecting amino acid residues with specific physical-chemical and structural attributes available in Blue Star Sting database Due to the rich repository of protein characteristics offered by BlueStar STING (BSS) platform [16][17][18][19], which is the latest version of SMS, has already been used to predict enzyme class [20], proteinligand analysis [21,22], protein mutant analysis [23,24], protein-protein interaction pattern analysis [25] and others [26,27]. In this work, BSS platform was used as a tool to predict a conformational epitope of Mut-II based on its physicochemical properties.…”