Stomach Carcinoma Incidence Patterns in the United States by Histologic Type and Anatomic Site

Wu, Hongyu; Rusiecki, Jennifer; Zhu, Kangmin; Potter, John F.; Devesa, Susan S.

doi:10.1158/1055-9965.epi-09-0250

Cited by 173 publications

(157 citation statements)

References 35 publications

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“…12 Male predominance was lost in patients younger than 30 years of age. Similar finding was observed by a study done by Wu H et al 13 According to the classification proposed by Lauren in 1965, gastric cancer has two histologic subtypes: Intestinal and Diffuse. 14 The most common type of gastric cancer in this study was intestinal type followed by mixed type and diffuse type.…”

Section: Discussionsupporting

confidence: 90%

“…Wu H et al in his study found 74% to be intestinal type and 16% diffuse type which concord with this study. 13 In this study diffuse type adenocarcinoma was seen in younger patients in comparison with intestinal-type cancer. Lauren himself observed a stronger male preponderance and older age at diagnosis for intestinal-typecancer than for diffusetype cancer 14 , which was corroborated by HanaiA et al 15 Prognostic factors on survival includes tumor location, depth of penetration, lymph node status, Lauren classification, histological grade, micro vessel invasion, type ofresection performed, and use of postoperative chemotherapy and radiation therapy.…”

Section: Discussionmentioning

confidence: 51%

“…Similar observation was documented by other studies. [13][14][15] Hepatoid adenocarcinoma (HAC) is a special type of extrahepatic adenocarcinoma, which has a striking morphologic similarity to hepatocellular carcinoma. Since itsfirst description in the stomach, which is the most common location, it has been described in different organs such as lung, pancreas, esophagus, papilla of Vater, colon, urinary bladder, renal pelvis, ovaries, uterus, and cervix.…”

Section: Discussionmentioning

confidence: 99%

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Incidence of gastric cancer, its subtypes, and correlation with Helicobacter Pylori

Kc¹,

Amatya²,

Lakhey

et al. 2013

J Pathol Nep

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Background: Gastric cancer is the fourth most commonly diagnosed cancer and the second most common cause of cancer related death worldwide. It is the common cause of cancer related death in Nepal. Helicobacter Pylori has been classifi ed as a defi nite carcinogen along with other factors. The aim of this study was to fi nd the incidence of gastric cancer among the patients undergoing upper gastroscopy, its various subtypes and association with Helicobacter Pylori. Materials and Methods:This is a retrospective and prospective study carried out at GRP Polyclinic and Kist Medical College Teaching Hospital. All the patients undergoing upper gastrointestinal endoscopy were included in this study. Data of all the gastric endoscopic biopsies done from June 2011 to January 2013 were collected and analyzed. All the biopsy specimens were processed routinely in histopathology laboratory. Specimens showing carcinoma were enrolled in this study and all the relevant demographic data were collected. Results:Out of 3395 biopsy cases; 49 cases (1.44%) were diagnosed as adenocarcinoma stomach. The overall mean age for carcinoma was 47.6 years with a mild male preponderance. Thirty cases (61.2%) were of intestinal type, (n=11; 22.4%) were of diffuse type and (n=8; 16.3%) were mixed type of adenocarcinoma. According to WHO classifi cation the most common subtype was tubular adenocarcinoma (n=35; 71.5%) followed by signet ring type (11 cases; 22.4%). Out of 49 cases of adenocarcinoma stomach 39 cases (79.5%) were Helicobacter Pylori positive. Conclusion:This study shows that gastric carcinoma is a male predominant neoplasm usually of old age but can occur at younger ages. It predominantly occurs in Helicobacter Pylori infected patients and H. Pylori eradication will help to decrease the incidence rate and mortality of stomach cancer.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Incidence of gastric cancer, its subtypes, and correlation with Helicobacter Pylori

Kc¹,

Amatya²,

Lakhey

et al. 2013

J Pathol Nep

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“…Recent studies have reported a continuing rise in the incidence of adenocarcinoma of the gastroesophageal junction (GEJ) despite a decline in the overall incidence of gastric carcinoma in Western countries [1,2]. Adenocarcinoma of the GEJ is defined as carcinoma centered within 5 cm of the anatomic GEJ, which is further classified into three distinct entities (types I, II, and III) according to the anatomic location of the tumor center [3,4].…”

Section: Introductionmentioning

confidence: 99%

Pattern of abdominal nodal spread and optimal abdominal lymphadenectomy for advanced Siewert type II adenocarcinoma of the cardia: results of a multicenter study

et al. 2012

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Background It remains uncertain whether radical lymphadenectomy combined with total gastrectomy actually contributes to long-term survival for Siewert type II adenocarcinoma of the cardia. We identified the pattern of abdominal nodal spread in advanced type II adenocarcinoma and defined the optimal extent of abdominal lymphadenectomy. Methods Eighty-six patients undergoing R0 total gastrectomy for advanced type II adenocarcinoma were identified from the gastric cancer database of 4,884 patients. Prognostic factors were investigated by multivariate analysis. The therapeutic value of lymph node dissection for each station was estimated by multiplying the incidence of were considered not beneficial to dissect, whereas there were substantial therapeutic benefits to dissecting the perigastric nodes of the upper half of the stomach in positions 1-3 and the second-tier nodes in positions 7 and 11. Conclusions Limited lymphadenectomy attained by proximal gastrectomy might suffice as an alternative to extended lymphadenectomy with total gastrectomy for obtaining On behalf

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“…In contrast, lower esophageal cancers and those involving the GEJ and proximal stomach have increased rapidly in incidence in Western countries [7]. As tumor site influences the operative approach required, this results in Western patients frequently requiring more invasive surgery.…”

Section: How Geography and Surgery Impact On Treatment Choicementioning

confidence: 99%

Adjuvant or neoadjuvant therapy for operable esophagogastric cancer?

2014

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Esophagogastric cancer encompasses proximal squamous cell carcinoma of the esophagus, distal esophageal/junctional adenocarcinoma of the esophagus and gastric adenocarcinoma. These diseases have different etiologies, geographic incidences and biologies. This review mainly focuses on the treatment of operable esophagogastric adenocarcinoma. In Asia, adjuvant chemotherapy is commonly used for patients with gastric cancer following the landmark ACTS-GC trial. In contrast, perioperative chemotherapy is a standard of care in many Western countries based on the results of the MAGIC trial.

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Stomach Carcinoma Incidence Patterns in the United States by Histologic Type and Anatomic Site

Abstract: Background: Using data from the U.S. National Cancer Institute's Surveillance, Epidemiology, and End Results program, we analyzed stomach carcinoma incidence patterns by both histologic type and anatomic site.

Cited by 173 publications

References 35 publications

Incidence of gastric cancer, its subtypes, and correlation with Helicobacter Pylori

Incidence of gastric cancer, its subtypes, and correlation with Helicobacter Pylori

Pattern of abdominal nodal spread and optimal abdominal lymphadenectomy for advanced Siewert type II adenocarcinoma of the cardia: results of a multicenter study

Adjuvant or neoadjuvant therapy for operable esophagogastric cancer?

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