Straightforward synthesis of quinazolin-4(3H)-ones via visible light-induced condensation cyclization

Abstract

Visible light was used as a readily available and renewable clean energy source for the green and metal catalyst free synthesis of quinazolin-4(3H)-ones. High and excellent yields of the desired products were obtained with good functional group tolerance.

An efficient and green synthesis of 2‐phenylquinazolin‐4(3H)‐ones using Brønsted acidic ionic liquid grafted onto silica

“…Phenylquinazolin-4(3H)-one41 White solid, mp. 231-233 °C FT-ATR-IR (4000-600 cm −1 ): 3350 (N H), 3058 (H-Csp 2 ), 1685 (C=O), 1590 (C=C), 1555 (C=N), 1325 (C N).1 H NMR (500 MHz, DMSO) ⊐ 12.86 (s, 1H), 8.55-8.45 (m, 3H), 8.18-8.15 (m, 1H), 8.08 (d, J = 7.5 Hz, 1H), 7.98-7.80 (m, 4H).…”