Strain-gauge plethysmography; theoretical and practical notes on a new design.

Brakkee, A. J. M.; Vendrik, A. J. H.

doi:10.1152/jappl.1966.21.2.701

Cited by 92 publications

(38 citation statements)

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“…2), removing the main objection previously held against mechanical calibration (Brakes &;Vendrik, 1966). Strain gauge plethysmography of the limb has been reported in which an electrical calibration has been advocated (Brakee &;Vendrik, 1966;Hallbook, Mansson &;Nilsen, 1970). However, mechanical calibration offers a very significant advantage in that it compensates for the effects# of tissue compression and displacement by the strands of the gauge.…”

Section: Methodsmentioning

confidence: 99%

An estimation of intracranial blood flow in the new‐born infant.

Cross¹,

Dear²,

Hathorn³

et al. 1979

The Journal of Physiology

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4. The jugular veins in the baby's neck are occluded by finger pressure and there follows an increase in skull volume, which is rapid at first, but which decreases exponentially as venous drainage diverts to non-occluded channels such as the vertebral venous plexus. At the instant of jugular occlusion the rate of skull volume increase is representative of the rate of flow in the jugular vessels prior to occlusion, and so provides an index of the relative magnitude of the intracranial blood flow. The method thus allows changes in intracranial blood flow to be followed. When occlusion is released cranial volume decreases, initially rapidly, but slowing exponentially as resting volume is regained.5. A theoretical model of the events occurring during the inflow and outflow phases has been developed, and a formula derived which allows an estimation to be made of the flow of blood through uncompressed channels. The measured value of jugular blood flow can then be augmented to an estimate of total intracranial flow.6. The mean cerebral blood flow of sixteen normal babies was estimated to be 40 ml. 100 g-1. min-' (S.D. = + 11t63).

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Section: Methodsmentioning

confidence: 99%

An estimation of intracranial blood flow in the new‐born infant.

Cross¹,

Dear²,

Hathorn³

et al. 1979

The Journal of Physiology

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show abstract

“…The plethysmograph (Model EC6, D.E. Hokanson) was calibrated according to the electrical method as previously described (19). Before the measurements began, the distal cuff was inflated to a suprasystolic pressure of 220 mmHg (20).…”

Section: Data Acquisitionmentioning

confidence: 99%

Effects of Acute Nitric Oxide Synthase Inhibition on Lower Leg Vascular Function in Chronic Tetraplegia

Fountaine

Radulovic

Cardozo

et al. 2009

The Journal of Spinal Cord Medicine

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Background/Objective: To improve our understanding of the lower-leg vascular responses of nitric oxide synthase inhibition in persons with tetraplegia. Participants: Six people with chronic tetraplegia and 6 age-matched controls. Methods: Lower-leg relative vascular resistance and venous volume variation were obtained by venous occlusion plethysmography and blood pressure by auscultation at baseline. Postintravenous infusion of the nitric oxide synthase inhibitor N G -nitro-L-arginine-methyl-ester (1 mg?kg 21) or placebo on separate days. Results: At baseline in the group with tetraplegia compared with controls, mean arterial pressure and relative vascular resistance of the leg were significantly lower. After nitric oxide synthase inhibition, mean arterial pressure and lower leg vascular resistance were significantly elevated in both groups. There were no group or intervention differences in venous volume variation. Conclusion: These preliminary results suggest that nitric oxide synthase inhibition with 1 mg?kg 21 N G -nitro-L-arginine-methyl-ester normalizes seated blood pressure and lower leg vascular resistance to control group baseline levels.

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“…The plethysmograph was calibrated as described by Brakkee and Vendrik. 16 Relative changes in calf volume during cu in¯ation and head-up tilt were expressed as percentages of those during supine rest, which method is supposed to re¯ect changes in venous volume. 17 Analysis Averaged values of circulatory variables during headup tilt and supine rest periods and the corresponding cerebral oxygenation changes were calculated from data gathered during the last 5 min of each period, Cerebral oxygenation during head-up tilt S Houtman et al provided a steady state existed.…”

Section: Measurementsmentioning

confidence: 99%

Systemic circulation and cerebral oxygenation during head-up tilt in spinal cord injured individuals

et al. 2000

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Objective: To compare tilt-induced alterations in cardiovascular homeostasis and cerebral oxygenation of spinal cord-injured (SCI) to able-bodied (AB) individuals. Design: Subjects underwent 10 min supine rest followed by 10 min 708 head-up tilt. The last 5 min of supine rest and head-up tilt were analyzed, provided a steady state existed. Subjects: SCI individuals (n=11), with lesions between C4 and T4, and AB individuals (n=10), all males and balanced for age and weight. Conclusion: SCI demonstrated a greater decrease of MAP and stroke volume with a similar decrease in cerebral oxygenation compared to AB. This suggests that although systemic circulation was less well regulated in SCI compared with AB, cerebral circulation in SCI was maintained as in AB.

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Strain-gauge plethysmography; theoretical and practical notes on a new design.

Cited by 92 publications

References 0 publications

An estimation of intracranial blood flow in the new‐born infant.

An estimation of intracranial blood flow in the new‐born infant.

Effects of Acute Nitric Oxide Synthase Inhibition on Lower Leg Vascular Function in Chronic Tetraplegia

Systemic circulation and cerebral oxygenation during head-up tilt in spinal cord injured individuals

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