The object of the research is the process of regional concentration of engineering organizations in Ukraine. The article discusses one of the reasons for the regional concentration of factors of production of Ukrainian organizations of the sphere of engineering. Research methodology is based on the definition of the difference by the module of the specific gravity of the distribution by regions of the factor and the result of its influence. If the corresponding difference is not minimal, then there is a weak link between the investigated factors. It is justified the hypothesis that an important reason for the regional concentration of factors of activity of organizations in the sphere of engineering is social, as well as scientific and technological and innovation infrastructure. As a result of the research, it was revealed that the regional location of industrial enterprises in Ukraine is not the main reason for the regional concentration of Ukrainian organizations in the engineering sphere. Customers and performers of project documentation interact without any problems even being in different regions of the country.