2016
DOI: 10.1002/elan.201600166
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Strategic Applications of Nanomaterials as Sensing Platforms and Signal Amplification Markers at Electrochemical Immunosensors

Abstract: Tremendous developments in electrochemical immunosensors have facilitated cost‐effective, rapid and robust detection of many analytes. Among the significant developments, electrochemical immunosensors capable of simultaneously detecting several analytes have begun to emerge. In addition, recent progress in materials science and engineering has yielded nanostructured materials of various geometries that were readily exploited to provide a compatible medium for many biomolecules in immunoassays. Applications of … Show more

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Cited by 44 publications
(23 citation statements)
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References 181 publications
(167 reference statements)
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“…extensively reviewed the progress of nanotechnology on glucose monitoring between 2003 to 2013 including either a macroelectrode fabricated with nanomaterials or a microelectrode array of nanomaterials on different substrates. In this aspect, we have recently published a Review involving strategic applications of nanomaterials at electrochemical immunosensors . However, in this section, we will only discuss physically small sensors used to detect glucose at a subcellular level.…”
Section: Disease Biomarker Detection At Structurally Small Electrodesmentioning
confidence: 99%
“…extensively reviewed the progress of nanotechnology on glucose monitoring between 2003 to 2013 including either a macroelectrode fabricated with nanomaterials or a microelectrode array of nanomaterials on different substrates. In this aspect, we have recently published a Review involving strategic applications of nanomaterials at electrochemical immunosensors . However, in this section, we will only discuss physically small sensors used to detect glucose at a subcellular level.…”
Section: Disease Biomarker Detection At Structurally Small Electrodesmentioning
confidence: 99%
“…Nanoparticles, such as semiconductor nanoparticles and metal oxide nanostructures, have been considered as potential signal labels to stimulate the development of signal amplification strategy for immunosensong [16,17]. The enormous signal enhancement associated with the use of nano labels provides the basis for ultrasensitive immunosensor and immunoassays with different measurement techniques [18].…”
Section: Nanoparticles As Signal Labels For Signal Amplificationmentioning
confidence: 99%
“…The chemical surface modification of the surfaces of such electrochemical sensors with nanomaterials can enhance these advantages. Nanomaterials which are approximately 1–100 nm in length compared with bulk materials composed of the same substance show remarkable differences in chemical and physical properties, such as unique electrical, optical, catalytic magnetic and thermal characteristics . Metallophthalocyanine (MPc) have a high chemical and thermal stability, electrical and optical properties and rich coordination chemistry.…”
Section: Introductionmentioning
confidence: 99%