The measurement and evaluation of performance are critical for the efficient and effective functioning of the economic system, because this allows for the analysis of the extent to which the defined objectives are achieved. Organizational performance is measured by different methods, both quantitative and qualitative. Many of the known methods for the evaluation and measurement of organizational performance take into account only financial indicators, while ignoring the non-financial ones. The integration of both indicators, through the combined application of multiple methods and the comparison of their results, should provide a more complete and objective picture of organizational performance. The Analytic Hierarchy Process (AHP) is a formal framework for solving complex decision-making problems, as well as a systemic procedure for the hierarchical presentation of the problem elements. The Data Envelopment Analysis (DEA) is a nonparametric approach based on linear programming, which allows for the calculation of the efficiency of decision-making units within a group of organizations. The work is an illustration of the method and framework of the combined use of the multi-criteria analysis methods for the measurement and evaluation of the performance of higher education institutions in the Republic of Serbia. The advantages of this approach are reflected in overcoming the shortcomings of a partial application of the AHP and the DEA methods by utilizing a new, hybrid, DEAHP (Data Envelopment Analytic Hierarchy Process) method. Performance evaluation through an integrated application of the AHP and the DEA methods provides more objective results and more reliable solutions to the observed problem, thus creating a valuable information base for high-quality strategic decision making in higher education institutions, both at the national level and at the level of individual institutions.Keywords: multi-criteria analysis, analytic hierarchy process, data envelopment analysis, organizational performance, higher education JEL Classification: C44, C61, D81, I23 Organizational performance is, in general, multidimensional and influenced by a number of factors, such as financial factors, as the indicators of the financial position of the organization, strategic qualitative factors, which determine the internal activities of the organization and their relationship with the market and economic factors, including the business environment, etc. The aggregation of all these factors into a composite, overall performance measure is a subjective and complex process depending on the value and preference systems of decision makers in the decision-making process. Creating a performance measurement system is, therefore, a complex task, and what is to be considered as an optimal performance measurement system will vary from one case to another (Tangen, 2005). In this regard, it is important to understand how performance measurement systems are developed and integrated into organizations' management models. These findings are fully cons...