This study explores the experiences of elementary school students with disabilities in learning computer programming and investigates the instructional strategies that enhance their learning within a culturally sustaining computer science curriculum. The case study was conducted in a special education classroom with multilingual Latinx students, utilizing an integrated computer science curriculum with a focus on community-based environmental literacy. The computer science projects aimed to promote peer collaboration, innovative problem-solving skills, and computational thinking skills. Students who typically do not interact with their peers engaged in rich collaboration during the computer science class. Additionally, students with behavioral and performance difficulties exhibited heightened engagement with the projects, channeling their creativity through computational thinking. Moreover, students applied the environmental knowledge they gained in class to real-world community settings. The instructional strategies employed by the teacher to support her students included engaging multiple senses, involving student experts, providing explicit instructions, modeling computational steps, and drawing connections between environmental and computational thinking concepts and students’ real-life situations. The results of this study underscore how a culturally sustaining computer science curriculum can empower diverse students, fostering inclusivity and leveraging their strengths. Furthermore, the results offer insight into effective teaching practices for supporting diverse students in a coding environment.