Extended Producer Responsibility (EPR) of Electronic Waste (e-waste) in Indonesia urgently needs comprehensive and enforceable regulations that hold the producers to have responsibility for the entire lifecycle of electronic products, ensuring proper management, and disposal. This study focuses on analyzing factors influencing the EPR of e-waste and emphasizes the critical need for such analysis in building enforceable regulations. This study utilizes the Analytic Network Process (ANP) to analyze the influencing factors. Key stakeholders, including experts, government officials, waste management authorities, producers, consumers, and academics, were involved as respondents. Data collection involved interviews and questionnaires. The study’s findings reveal that administrative instruments are considered a priority factor in the implementation of EPR for e-waste (0.368), followed closely by economic factors (0.362) and informative factors (0.271). Specifically, the collection aspect of administrative instruments emerges as the most dominant factor (0.387). In terms of economic and informative instruments, priority factors include product development subsidies (0.278) and awareness campaigns targeting producers (0.332). Furthermore, all respondents prefer to involve producer responsibility organizations in the EPR mechanism (0.343). By understanding the significant influencing factors, policymakers can focus on strengthening administrative instruments, offering economic incentives, and enhancing information dissemination. The involvement of producer responsibility organizations also emerges as a crucial aspect of effective EPR of e-waste implementation in Indonesia.