Strategies for preventing side effects of systemic opioid in postoperative pediatric patients

Jitpakdee, Thanaporn; Mandee, Sahatsa

doi:10.1111/pan.12420

Cited by 56 publications

(65 citation statements)

References 64 publications

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“…4 In pediatric patients, aggressive and proactive pain management is recommended perioperatively 5 ; however, because of opioid-related adverse effects, strategies minimizing the amount of opioid consumption are required. 6 Regional anesthesia with ultrasound guidance, such as peripheral nerve blocks 7 that can be placed safely under general anesthesia or deep sedation, 8 is increasingly used in pediatric patients. Therefore, surgical site-specific peripheral regional anesthesia was considered for treating post-USRM pain.…”

mentioning

confidence: 99%

Postoperative Analgesic Effect of Ultrasound-Guided Intermediate Cervical Plexus Block on Unipolar Sternocleidomastoid Release With Myectomy in Pediatric Patients With Congenital Muscular Torticollis

Joe

Park

Ahn

et al. 2018

Regional Anesthesia and Pain Medicine

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mentioning

confidence: 99%

Postoperative Analgesic Effect of Ultrasound-Guided Intermediate Cervical Plexus Block on Unipolar Sternocleidomastoid Release With Myectomy in Pediatric Patients With Congenital Muscular Torticollis

Joe

Park

Ahn

et al. 2018

Regional Anesthesia and Pain Medicine

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“…Thus, it is meaningful for the reduction of opioid analgesics consumption in children. Some researchers have suggested that minimizing the dose of opioid analgesics could reduce the side effects (30). The previous meta-analyses in adult have demonstrated the significant reduction of opioid usage in regional anesthesia treated adults group while comparing with placebo treated group, and the side effect of opioids such as nausea, sedation, and pruritus were reduced due to the lower opioid consumption (14,31,32).…”

Section: Discussionmentioning

confidence: 95%

Transversus Abdominis Plane Block to Alleviate Postoperative Pain in Children: A Meta-Analysis of Randomized Controlled Trials

Li¹,

Li²,

Xing³

et al. 2015

J Anesth Perioper Med

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Background: Transversus abdominis plane (TAP) block has been applied as one of multimodal approaches to alleviate postoperative pain in children. The aim of this meta-analysis was to determine the effect of TAP block on postoperative pain management for children who underwent surgery. Methods: The randomized controlled trials (RCTs) which evaluated the analgesia effect of TAP block in children who underwent surgery were searched on the databases of Medline, Embase, the Cochrane Controlled Trials Register and Google Scholar. The RCTs which compared the analgesic effect of TAP block group with control group (placebo or "no treatment") in children were included. Postoperative opioid consumption (48 hours) was considered as the primary outcomes. The secondary outcomes included the number of children needed postoperative opioid analgesia rescue, the time to first analgesic administration (hours) and pain score. The risk ratios (RR), weighted mean differences (WMDs), and their corresponding 95% con fi dence intervals (95% CIs) were calculated for both dichotomous and continuous outcomes. Results: Five RCT trials with 257 children met our criteria and were included in the analysis. Compared with the control group, TAP block reduced the 48 hours morphine consumption by 0.03 mg/kg (95% CI -0.05 to -0.00, P=0.03, 159 children in 3 RCTs). Besides, the non-signi fi cant reductions were shown in the number of children needed postoperative opioid analgesia rescue (217 children in 4 RCTs) and time to first analgesic administration (hours, 184 children in 3 RCTs). Conclusions: TAP block is one of the safe and effective multimodal-approaches to alleviate postoperative pain in children. Specially, when the TAP block was used, it can significantly reduce the opioid consumption, which may avoid the occurrence of dose-dependent side effects of opioid drugs.

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“…A wide range of drugs have been associated with central emetic side effects and secondary effects due to gastric irritation [ 8 ]. Among the drugs with central emetic effects are opiate analgesics [ 85 ] and chemotherapeutics agents [ 86 ]. Other drugs can induce vomiting secondary to gastric irritation, such as aspirin, diuretics, and alcohol [ 5 ].…”

Section: Side Effect Of Drugsmentioning

confidence: 99%

Causes of Dental Erosion: Intrinsic Factors

Scaramucci

Carvalho

Hara

et al. 2015

Dental Erosion and Its Clinical Management

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The consequences of the severe wear caused by intrinsic erosion, in addition to the high cost and complexity of the treatment to restore severely worn dentition, support the importance of early diagnosis and implementation of preventive/therapeutic measures. Dental professionals must be aware of the signs and symptoms of the disease, as well as all the conditions that may lead to the presence of gastric juice in the mouth, so they can make the referral to the appropriate medical specialist. In this chapter, the main clinical conditions associated with intrinsic erosion are presented and its clinical signs and symptoms discussed from a clinical perspective.

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Strategies for preventing side effects of systemic opioid in postoperative pediatric patients

Cited by 56 publications

References 64 publications

Postoperative Analgesic Effect of Ultrasound-Guided Intermediate Cervical Plexus Block on Unipolar Sternocleidomastoid Release With Myectomy in Pediatric Patients With Congenital Muscular Torticollis

Postoperative Analgesic Effect of Ultrasound-Guided Intermediate Cervical Plexus Block on Unipolar Sternocleidomastoid Release With Myectomy in Pediatric Patients With Congenital Muscular Torticollis

Transversus Abdominis Plane Block to Alleviate Postoperative Pain in Children: A Meta-Analysis of Randomized Controlled Trials

Causes of Dental Erosion: Intrinsic Factors

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