Strategies for Translational Research in the United Kingdom

Soderquest, Katrina; Lord, Graham M.

doi:10.1126/scitranslmed.3001129

Cited by 10 publications

(7 citation statements)

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“…With the aim of creating a national infrastructure for translating scientific breakthroughs into new treatments for patients, NIHR has awarded £2.2bn (€2.5bn; $2.9bn) of UK taxpayers’ funding for translational research to biomedical research centres and units—partnerships between NHS organisations and universities. The strategic objectives, scope, and magnitude of funding of these centres have parallels with the Clinical and Translational Science Awards Program of the US National Institutes of Health 5…”

Section: National Translational Research Infrastructurementioning

confidence: 99%

Effect of Athena SWAN funding incentives on women’s research leadership

Ovseiko

Taylor²,

Gilligan

et al. 2020

BMJ

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Is it difficult being a woman scientist?" the biochemist Dorothy Crowfoot Hodgkin was asked at high table dinner in an Oxford college by the man sitting next to her. "Not since I won the Nobel Prize," she replied. 1 In 1964, the British press had reacted to her award with the headlines: "Oxford housewife wins Nobel" and "British woman wins Nobel Prize-£18 750 prize to mother of three." 2 While such overtly sexist treatment of female scientists by the media is now rare, progress towards gender equality in universities has been astonishingly slow. A UK parliamentary inquiry into women in scientific careers found that with only 17% of professors in science, technology, engineering, and mathematics (STEM) in 2011-12 women were still under-represented at senior levels across all STEM disciplines. 3 Concerned with the sustainability of increasing the scientific workforce, the inquiry concluded that efforts to inspire more women into science were wasted if they were subsequently disadvantaged compared with men and recommended that universities should do more to support and retain women in scientific careers. 3

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Section: National Translational Research Infrastructurementioning

confidence: 99%

Effect of Athena SWAN funding incentives on women’s research leadership

Ovseiko

Taylor²,

Gilligan

et al. 2020

BMJ

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“…As a result, 51 centres for translational research were established during this period [61][62][63]. In the UK, the NIHR established Biomedical Research Centres, analogous to the CTS institutes in the US and the Government awarded the title of Academic Health Science Centres to institutions in which CTS and the clinical mission were integrated [64].…”

Section: Interdisciplinary Supportmentioning

confidence: 99%

Academia Europaea Position Paper on Translational Medicine: The Cycle Model for Translating Scientific Results into Community Benefits

Hegyi

Petersen

Holgate

et al. 2020

JCM

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Introduction: Translational science has gained prominence in medicine, but there is still much work to be done before scientific results are used optimally and incorporated into everyday health practice. As the main focus is still on generating new scientific data with financial resources primarily available for that purpose, other activities that are necessary in the transition from research to community benefit are considered less needy. The European Statistical Office of the European Commission has recently reported that 1.7 million people under 75 years of age died in Europe in 2016, with around 1.2 million of those deaths being avoidable through effective primary prevention and public health intervention. Therefore, Academia Europaea, one of the five Pan-European networks that form SAPEA (Science Advice for Policy by European Academies), a key element of the European Commission’s Scientific Advice Mechanism (SAM), has launched a project to develop a model to facilitate and accelerate the utilisation of scientific knowledge for public and community benefit. Methods: During the process, leaders in the field, including prominent basic and clinical researchers, editors-in-chief of high-impact journals publishing translational research articles, translational medicine (TM) centre leaders, media representatives, academics and university leaders, developed the TM cycle, a new model that we believe could significantly advance the development of TM. Results: This model focuses equally on the acquisition of new scientific results healthcare, understandable and digestible summation of results, and their communication to all participants. We have also renewed the definition in TM, identified challenges and recommended solutions. Conclusion: The authors, including senior officers of Academia Europaea, produced this document to serve as a basis for revising thinking on TM with the end result of enabling more efficient and cost-effective healthcare.

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“…Two types of biomedical research centres (BRCs) have been developed in the UK, which are playing critical roles for advancement of TR, i.e . Comprehensive BRCs and Specialist BRCs 13 . Another initiative 'Translation Together' is to link the gap of new innovations between basic fundamental discoveries related to human disease and the delivery of new therapeutic options to the patients.…”

Section: International Scenario - Translational Research Initiativesmentioning

confidence: 99%