Introduction Addressing strategies of coping among community psychiatric nurses (CPNs) could help increase an individual’s ability to cope effectively and as a result, reduce experienced levels of stress. It is known that the level of work stress experienced by CPNs is remarkably high, because psychiatric nurses face more intense relationships with their patients, trying to prevent self-harm, and most at times face challenging situations with aggressive patient behaviors in the working environment. Therefore, the study aimed to explore the coping strategies employed by CPNs during healthcare delivery in the community. Methods An exploratory qualitative study design using an interpretative approach was employed. A total of 13 CPNs were purposively sampled, and data gathered through individual interviews using an interview guide. The interviews were audio-taped, transcribed verbatim and analyzed thematically, describing some of the coping strategies employed by CPNs in Ghana. Results Participants’ ages ranged from 26-60years. They comprised 3 males and 10 females. An inductive thematic analysis identified the following major coping strategies of community psychiatric nurses; self-disguise (wearing of mufti), reliance on religious faith, self-motivation and reduction in the number of home visits. Conclusion Coping strategies among community psychiatric nurses are essential for both individuals and organisations. Thus, community psychiatric nurses must acquire personal-mastery coping strategies such as the reduction in the number of home visits, self-disguise (wearing mufti) the use of faith to motivate themselves in the face the challenging working environment. The coping strategies adopted by community psychiatric nurses was not to only help them deliver care, but also as a way of protecting the clients so that people would not tag them as ‘mental patients’