Strategies to Investigate Signal Transduction Pathways with Mathematical Modelling

Mass Spec

“…In cells, biological responses are coordinated through signaling networks composed of interacting proteins that deal with (1) the reception and emission of chemical signals within and between cells, (2) the modulation and integration of signals which control gene expression and ultimately cell function, and (3) the control and coordination of metabolic processes responsible for the intracellular bioenergetics and the biosynthesis (Vera et al 2010).…”

Detection and Analysis of Critical Dynamic Properties of Oligodendrocyte Differentiation

“…As an interdisciplinary approach in the life sciences, systems biology aims to integrate experiments in iterative cycles with computational and mathematical modeling, simulations and theory [21]. The intersection between neurobiology and systems biology can be defined as systems neurobiology [22].…”