We study mean curvature flow of Lagrangians L ⊂ C n that are cohomogeneity-one under a compact Lie group G ≤ SU(n) acting linearly on C n . Each such Lagrangian necessarily lies in a level set µ −1 (ξ) of the standard moment map µ : C n → g * , and mean curvature flow preserves this containment.We classify all cohomogeneity-one self-similarly shrinking, expanding and translating solutions to the flow, as well as cohomogeneity-one smooth special Lagrangians lying in µ −1 (0). Restricting to the case of almost-calibrated flows in the zero level set µ −1 (0), we classify finite-time singularities, explicitly describing the Type I and Type II blowup models. Finally, given any cohomogeneity-one special Lagrangian submanifold in µ −1 (0), we show it occurs as the Type II blowup model of a Lagrangian MCF singularity, thereby providing infinitely many previously unobserved singularity models. Throughout, we give explicit examples of suitable group actions, including a complete list in the case of G simple.