Streak camera: a multidetector for diffuse optical tomography

Zint, C.V.; Uhring, Wilfried; Torregrossa, Murielle; Cunin, B.; Poulet, P.

doi:10.1364/ao.42.003313

Cited by 21 publications

(9 citation statements)

References 16 publications

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“…This method has good throughput, but poor time resolution owing to the relatively low modulation speeds that are possible in tissue. Alternatively, measurements can be performed in the time domain by directly comparing pulsed laser light to a electrical reference signal using a streak camera [9,10] or a time correlated single photon counter (TCSPC) [7]. Both of these techniques suffer from high cost, require complicated electronics and have low throughput.…”

Section: Introductionmentioning

confidence: 99%

Imaging beyond the ballistic limit in coherence imaging using multiply scattered light

Giacomelli¹,

Wax²

2011

Opt. Express

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We present an imaging system based on low coherence interferometric detection of multiply scattered light for extended depth imaging into highly scattering media. By incorporating angle-resolved detection, coherence imaging with multiply scattered photons is shown to be both feasible and potentially superior to existing techniques for performing time-resolved measurements of scattered light. Imaging is demonstrated through nearly 100 mean free paths of scattering phantom in a single-ended geometry. The resolution and imaging contrast are compared to those obtained with conventional OCT systems which chiefly detect singly scattered light.

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Section: Introductionmentioning

confidence: 99%

Imaging beyond the ballistic limit in coherence imaging using multiply scattered light

Giacomelli¹,

Wax²

2011

Opt. Express

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“…Indeed, if one wants to achieve a TR measurement of [oxCCO], it requires a multi-wavelength system, which is challenging for this type of instrumentation. One could use a streak camera for the detector, but it would be limited to the TR dimension with either the spectral [57] or spatial [58] dimension, but not both. Besides the streak cameras, the most widespread technology for TR measurement is time-correlated single-photon counting (TCSPC) [43].…”

Section: Discussionmentioning

confidence: 99%

Broadband time-resolved multi-channel functional near-infrared spectroscopy system to monitor in vivo physiological changes of human brain activity

Lange¹,

Peyrin²,

Montcel³

2018

Appl. Opt.

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We have developed a broadband time-resolved multi-channel near-infrared spectroscopy system that can monitor the physiological responses of the adult human brain. This system is composed of a supercontinuum laser for the source part and of an intensified charge-coupled device camera coupled with an imaging spectrometer for the detection part. It allows the detection of the spectral, from 600 to 900 nm, and spatial dimensions as well as the arrival time of photon information simultaneously. We describe the setup and its characterization in terms of temporal instrument response function, wavelength sensitivity, and stability. The ability of the system to detect the hemodynamic response is then demonstrated. First, an in vivo experiment on an adult volunteer was performed to monitor the response in the arm during a cuff occlusion. Second, the response in the brain during a cognitive task was monitored on a group of five healthy volunteers. Moreover, looking at the response at different time windows, we could monitor the hemodynamic response in depth, enhancing the detection of the cortical activation. Those first results demonstrate the ability of our system to discriminate between the responses of superficial and deep tissues, addressing an important issue in functional near-infrared spectroscopy.

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“…Certain versions of these techniques can also be performed very rapidly, at upwards of 50 Hz, to obtain information about pulsatile hemodynamics in living tissue [97]. Some DOS/DOT techniques, such as those involving streak cameras, can even enable near-ps scale temporal resolution to measure photon time-of-flight distributions in tissue [98, 99]. NLO methods provide microscopic spatial resolution for imaging of structures such as cells and collagen fibers in vivo [91].…”

Section: Summary Perspectives and Conclusionmentioning

confidence: 99%

Optical methods for quantitative and label-free sensing in living human tissues: principles, techniques, and applications

Wilson

Vishwanath

Mycek

2016

Advances in Physics: X

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We present an overview of quantitative and label-free optical methods used to characterize living biological tissues, with an emphasis on emerging applications in clinical tissue diagnostics. Specifically, this review focuses on diffuse optical spectroscopy, imaging, and tomography, optical coherence-based techniques, and non-linear optical methods for molecular imaging. The potential for non- or minimally-invasive assessment, quantitative diagnostics, and continuous monitoring enabled by these tissue-optics technologies provides significant promise for continued clinical translation.

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Streak camera: a multidetector for diffuse optical tomography

Cited by 21 publications

References 16 publications

Imaging beyond the ballistic limit in coherence imaging using multiply scattered light

Imaging beyond the ballistic limit in coherence imaging using multiply scattered light

Broadband time-resolved multi-channel functional near-infrared spectroscopy system to monitor in vivo physiological changes of human brain activity

Optical methods for quantitative and label-free sensing in living human tissues: principles, techniques, and applications

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