Streaming Detection for Evaluation of Indeterminate Sonographic Breast Masses: A Pilot Study

Soo, Mary Scott; Ghate, Sujata V.; Baker, Jay A.; Rosen, Eric L.; Walsh, Ruth; Warwick, Brenda N.; Ramachandran, Aditya; Nightingale, Kathryn R.

doi:10.2214/ajr.05.0005

Cited by 15 publications

(17 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…material, properties (Nightingale et al 2002; Palmeri et al 2005b). Radiation force-based methods have been demonstrated in recent years for differentiating tissue structure via mechanical property in varied applications, including discrimination of breast lesions (Alizad et al 2004; Soo et al 2006), myocardial RF ablations (Fahey et al 2005a), abdominal aortic aneurysms (Mozes et al 2005), thermally and chemically induced lesions (Bercoff et al 2004), abdominal organs (Fahey et al 2005b), the gastrointestinal track (Palmeri et al 2005a), liver (Nightingale 2006), thrombosis (Viola et al 2004), and myocardium (Bradway et al 2007; Hsu et al 2007). In addition, acoustic radiation force has been effective for delineating tissue structure in human peripheral arteries (Dahl et al 2006; Trahey et al 2004) as well as pig arteries (Pislaru et al 2008; Zhang and Greenleaf 2007; Zhang et al 2006).…”

Section: Introductionmentioning

confidence: 99%

ARFI Imaging for Noninvasive Material Characterization of Atherosclerosis Part II: Toward In Vivo Characterization

Behler

Nichols

Zhu

et al. 2009

Ultrasound in Medicine & Biology

View full text Add to dashboard Cite

Seventy percent of cardiovascular disease (CVD) deaths are attributed to atherosclerosis. Despite their clinical significance, nonstenotic atherosclerotic plaques are not effectively detected by conventional atherosclerosis imaging methods. Moreover, conventional imaging methods are insufficient for describing plaque composition, which is relevant to cardiovascular risk assessment. Atherosclerosis imaging technologies capable of improving plaque detection and stratifying cardiovascular risk are needed. Acoustic Radiation Force Impulse (ARFI) ultrasound, a novel imaging method for noninvasively differentiating the mechanical properties of tissue, is demonstrated for in vivo detection of nonstenotic plaques and plaque material assessment in this pilot investigation. In vivo ARFI imaging was performed on four iliac arteries: 1) of a normocholesterolemic pig with no atherosclerosis as a control, 2) of a familial hypercholesterolemic pig with diffuse atherosclerosis, 3) of a normocholesterolemic pig fed a high-fat diet with early atherosclerotic plaques and 4) of a familial hypercholesterolemic pig with diffuse atherosclerosis and a small, minimally-occlusive plaque. ARFI results were compared to spatially matched immunohistochemistry, showing correlations between elastin and collagen content and ARFI-derived peak displacement and recovery time parameters. Faster recoveries from ARFI-induced peak displacements and smaller peak displacements were observed in areas of higher elastin and collagen content. Importantly, spatial correlations between tissue content and ARFI results were consistent and observable in both large and highly evolved as well as small plaques. ARFI imaging successfully distinguished nonstenotic plaques, while conventional B-Mode ultrasound did not. This work validates the potential relevance of ARFI imaging as a noninvasive imaging technology for in vivo detection and material assessment of atherosclerotic plaques.

show abstract

Section: Introductionmentioning

confidence: 99%

ARFI Imaging for Noninvasive Material Characterization of Atherosclerosis Part II: Toward In Vivo Characterization

Behler

Nichols

Zhu

et al. 2009

Ultrasound in Medicine & Biology

View full text Add to dashboard Cite

show abstract

“…This phenomenon can be observed in human cysts and can assist in diagnosis of fluid-filled cyst versus solid tumor using the pulsed-Doppler mode to produce and observe the fluid motion (Soo et al, 2006). This phenomenon can be observed in human cysts and can assist in diagnosis of fluid-filled cyst versus solid tumor using the pulsed-Doppler mode to produce and observe the fluid motion (Soo et al, 2006).…”

Section: Nonthermal Tissue Interaction and Bioeffects In Dusmentioning

confidence: 96%

Biological Effects in Diagnostic Ultrasound

Miller

2014

Comprehensive Biomedical Physics

View full text Add to dashboard Cite

“…In addition to IVUS elastography, several other methods of imaging mechanical properties of tissue via ultrasound currently exist, including Non-Invasive Vascular Elastography (NIVE), Vibroacoustography, and Acoustic Radiation Force Impulse Imaging [10][11][12][13][14][15][16][17][18]. NIVE utilizes a speckle model to calculate the Von Mises coefficient and has been demonstrated in vitro to be capable of differentiating phantoms of different mechanical property [10].…”

Section: Introductionmentioning

confidence: 99%

“…By measuring bending wave propagation, Vibroacoustography has been demonstrated for estimating the elastic modulus in porcine arterial walls, ex vivo [11]. ARFI imaging has been described in great detail by [12][13][14][15][16][17][18]. Briefly, two-dimensional (2D) ARFI imaging is performed by directing an impulse of acoustic radiation force across a lateral FOV.…”

Section: Introductionmentioning

confidence: 99%

“…Measured ARFI induced displacement profiles are then analyzed for peak displacement, recovery rate, and other parameters indicative of tissue mechanical property. ARFI imaging has been demonstrated in application to differentiating breast cysts from solid masses [12][13][14], assessing the status of the vitreous humor [15], measuring blood clotting times [16], interrogating organs in the abdomen [17], and imaging human arteries [18].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

6G-5 ARFI Ultrasound for Characterizing Atherosclerosis

Dumont

Behler

Nichols

et al. 2006

2006 IEEE Ultrasonics Symposium

View full text Add to dashboard Cite

Cardiovascular disease (CVD) is the leading cause of death in the United States, with coronary artery disease and stroke alone accounting for 70% of CVD mortalities. Given this tremendous human impact, imaging technologies that enhance CVD outcomes by enabling earlier disease detection, monitoring the effects of therapeutic interventions, and delineating disease progression or regression are in critical need. We hypothesize that Acoustic Radiation Force Impulse (ARFI) ultrasound is efficacious for noninvasive characterization of atherosclerotic plaque and arterial walls in CVD assessment. To test this hypothesis, we performed ARFI imaging in three iliac arteries: 1) an excised familial hypercholesterolemic (FH) pig iliac with a raised focal atherosclerotic plaque, 2) an in vivo FH pig iliac with diffuse atherosclerosis, and 3) an in vivo control pig iliac with no known disease. In all three cases, our ARFI results were compared to matched immunohistochemistry, which showed a spatial correlation between collagen and elastin content and tissue mechanical property. This work supports the merit of additional investigations into ARFI imaging as a noninvasive, in vivo imaging technology for characterizing atherosclerotic plaque and arteries.

show abstract

Streaming Detection for Evaluation of Indeterminate Sonographic Breast Masses: A Pilot Study

Abstract: The streaming detection technique improved differentiation of cysts from solid masses in indeterminate lesions and has potential for reducing the number of recommended cyst aspirations for the diagnosis of indeterminate breast masses.

Cited by 15 publications

References 7 publications

ARFI Imaging for Noninvasive Material Characterization of Atherosclerosis Part II: Toward In Vivo Characterization

ARFI Imaging for Noninvasive Material Characterization of Atherosclerosis Part II: Toward In Vivo Characterization

Biological Effects in Diagnostic Ultrasound

6G-5 ARFI Ultrasound for Characterizing Atherosclerosis

Contact Info

Product

Resources

About