Strength of Relationships of the Pulse Wave Velocity and Central Hemodynamic Indices With the Serum N-Terminal Fragment B-Type Natriuretic Peptide Levels in Men

Correlations of arterial stiffness/central hemodynamics with serum cardiac troponin T and natriuretic peptide levels in a middle-aged male worksite cohort

“…The Atherosclerosis Risk in Communities (ARIC) Study also reported similar findings [5]. While several studies have demonstrated the existence of an association between increased arterial stiffness/abnormal central hemodynamics and elevated serum natriuretic peptide levels [12,13], no study has clarified the difference in the association with arterial stiffness/central hemodynamics between serum cTnT levels and serum NT-proBNP levels. Existence of such a difference might serve as at least one of the explanations for the independency of the predictive values of the two serum markers for future cardiovascular events.…”

“…Previously, we reported the existence of a significant relationship between the arterial stiffness/central hemodynamics and serum NT-proBNP levels in a middle-aged male worksite cohort [12]. Then, in the same cohort of our previous study (middle-aged male subjects working at a construction company), the present cross-sectional study was conducted to clarify whether increased arterial stiffness/abnormal central hemodynamics might be associated as strongly with minimal elevations of the serum cTnT levels as with elevations of the serum NTproBNP levels.…”

“…Subjects falling under the following criteria were excluded from the study [12,14,15]: (1) ankle/brachial systolic blood pressure index of less than 0.95; (2) presence of atrial fibrillation;…”

Endovascular Aortic Repair Increases Vascular Stiffness and Alters Cardiac Structure and Function

“…Finally, baPWV may not be accurate in patients with AAA and TAA. 31 However, the length of the aortic aneurysm is a relatively small fraction of the distance between the brachial and ankle arteries and measurement of baPWV may not be strongly influenced by aortic aneurysm. This hypothesis is partly explained by the lack of a difference in baPWV between patients with AAA and matched controls.…”

Vascular Dysfunction: A Key Player in Chronic Cardio-renal Syndrome

“…3). Recently, we demonstrated that the central pulse pressure, rather than the peripheral pulse pressure, is a significant determinant of elevation of the serum natriuretic peptide levels, a marker of cardiac afterload (29).…”