Strengthening mechanism and biocompatibility of degradable Zn-Mn alloy with different Mn content

Zhu, Xinglong; Ren, Tiantian; Guo, Peng; Yang, Lijing; Shi, Yixuan; Sun, Wan‐chang; Song, Zhenlun

doi:10.1016/j.mtcomm.2022.103639

Cited by 10 publications

(19 citation statements)

References 57 publications

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“…The second phase has a key influence on grain refinement. During the grain refinement of Zn alloys, the second phase exerts a pinning effect at grain boundaries, stabilizing them and inhibiting the growth of newly refined grains [2,3]. As a result, during the plastic deformation of Zn alloys, the grain size decreases and the strength of the alloy changes.…”

Section: Discussionmentioning

confidence: 99%

“…However, the relationship between grain size and strength of Zn alloys does not exactly follow the rule. The strength of the Zn alloy increases when the manganese content in the Zn-Mn alloy is increased to refine the grain [2]. It has been found that for Zn alloys refining the extruded Zn-Mn, Zn-Cu, and Zn-Ag alloys by stretching and ECAP did not increase their strength [3,18].…”

Section: Discussionmentioning

confidence: 99%

“…where ρ GND is the geometrically necessary dislocation (GND) density of the measured point, ∆δ indicates the local orientation error, µ is the unit length of the point, and b indicates the Burgers vector whose magnitude is a constant of Zn [2]. The local orientation error is calculated as:…”

Section: Discussionmentioning

confidence: 99%

“…As a medical degradable metal, Zn and its alloys have a more suitable degradation rate than magnesium-and Ferume-based alloys. Zn also has good biocompatibility [2][3][4][5]. Therefore, Zn alloys are currently used in biodegradable implants, such as vascular stents [6,7], gastrointestinal anastomosis staples [8], and bone plates [9].…”

Section: Introductionmentioning

confidence: 99%

“…However, Zn's mechanical properties and machinability are relatively poor due to its crystalline structure (hexagonal close-packed) [4,10]. Current research is dedicated to improving the mechanical properties of Zn alloys, which is usually realized by adding different elements to Zn alloy via casting to create binary and multiple alloys such as Zn-Mn [2], Zn-Cu [11], and Zn-Mg [12]. Among all the elements, lithium (Li) is particularly effective in increasing the strength of Zn alloys; the strength of Zn-Li alloys is comparable with that of pure titanium and stainless steel [13,14].…”

Section: Introductionmentioning

confidence: 99%

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Strengthening Mechanism of Rotary-Forged Deformable Biodegradable Zn-0.45Li Alloys

et al. 2023

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The use of zinc (Zn) alloys as a biodegradable metal for medical purposes has been a popular research topic. This study investigated the strengthening mechanism of Zn alloys to enhance their mechanical properties. Three Zn-0.45Li (wt.%) alloys with different deformation amounts were prepared by rotary forging deformation. Their mechanical properties and microstructures were tested. A simultaneous increase in strength and ductility was observed in the Zn-0.45Li alloys. Grain refinement occurred when the rotary forging deformation reached 75.7%. The surface average grain size reached 1.19 ± 0.31 μm, and the grain size was uniformly distributed. Meanwhile, the maximum elongation of the deformed Zn-0.45Li was 139.2 ± 18.6%, and the ultimate tensile strength reached 426.1 ± 4.7 MPa. In situ tensile tests showed that the reinforced alloys still broke from the grain boundary. Continuous and discontinuous dynamic recrystallization during severe plastic deformation produced many recrystallized grains. During deformation, the dislocation density of the alloy first increased and then decreased, and the texture strength of the (0001) direction increased with deformation. Analysis of the mechanism of alloy strengthening showed that the strength and plasticity enhancement of Zn-Li alloys after macro deformation was a combination of dislocation strengthening, weave strengthening, and grain refinement rather than only fine-grain strengthening as observed in conventional macro-deformed Zn alloys.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Strengthening Mechanism of Rotary-Forged Deformable Biodegradable Zn-0.45Li Alloys

et al. 2023

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Mechanical Properties, Degradation Behavior, and Cytocompatibility of Zn–Mg–Graphene Nanoplatelets Composite for Orthopedic‐Implant Applications

Kabir,

Lin,

Munir

et al. 2023

Adv Eng Mater

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Zinc (Zn)‐based materials reveal inadequate mechanical properties as orthopedic biodegradable implantable materials, which limits their biomedical applications. Herein, Zn–xMg (magnesium) composites (x = 0.5, 1.0, 1.5, and 2.0 wt%) reinforced with 0.2 wt% graphene nanoplatelets (GNP) are obtained via powder metallurgy and hot‐pressing sintering. The addition of 0.5–2.0 wt% Mg into Zn–0.2 wt% GNP composite resulted in the formation of Mg2Zn11 and MgZn2 phases without any additional intermetallic carbide phases. The hot‐pressing sintered (HPS) Zn–0.5Mg–0.2GNP composite exhibits a compressive yield strength of 169 ± 18 MPa, an ultimate compressive strength of 270 ± 39 MPa, a compressive strain of 17 ± 6%, and a microhardness of 86 ± 2 HV. Electrochemical corrosion testing reveals that corrosion resistance of HPS Zn–xMg–0.2GNP composites decreases with increasing Mg content, while immersion tests in Hanks’ balanced salt solution for 30 d indicate that the degradation rate increases from 0.032 to 0.141 mm y−1 by increasing Mg content from 0 to 2.0 wt%. In vitro cytotoxicity assessments using SaOS2 human osteoblast cells show >90% viability following exposure over 5 d to 12.5% extract concentrations of all HPS composites. The HPS Zn–0.5Mg–0.2GNP composite exhibits the appropriate material properties for biodegradable bone‐implant applications.

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In vitro performance of a biodegradable zinc alloy adjustable-loop cortical suspension fixation for anterior cruciate ligament reconstruction

Wang,

Shi,

Zhong

et al. 2024

Int J Miner Metall Mater

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Strengthening mechanism and biocompatibility of degradable Zn-Mn alloy with different Mn content

Cited by 10 publications

References 57 publications

Strengthening Mechanism of Rotary-Forged Deformable Biodegradable Zn-0.45Li Alloys

Strengthening Mechanism of Rotary-Forged Deformable Biodegradable Zn-0.45Li Alloys

Mechanical Properties, Degradation Behavior, and Cytocompatibility of Zn–Mg–Graphene Nanoplatelets Composite for Orthopedic‐Implant Applications

In vitro performance of a biodegradable zinc alloy adjustable-loop cortical suspension fixation for anterior cruciate ligament reconstruction

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