Strengthening of Mg based alloy through grain refinement for orthopaedic application

Nayak, Soumyaranjan; Bhushan, Bharat; Jayaganthan, R.; Gopinath, P.; Agarwal, R.D.; Lahiri, Debrupa

doi:10.1016/j.jmbbm.2015.12.010

Cited by 94 publications

(51 citation statements)

References 46 publications

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“…Decreasing the metallic grain size within the material volume, either by alloying elements, SPD methods, such as extrusion, equal channel angular pressing (ECAP) and high-pressure torsion (HPT) or PM, leads to increase of hardness, tensile and yield strength, but the plasticity of the material was shown to be decreased [6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Characterization of Powder Metallurgy Processed Pure Magnesium Materials for Biomedical Applications

Zapletal

Březina

Krystýnová

et al. 2017

Metals

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Magnesium with its mechanical properties and nontoxicity is predetermined as a material for biomedical applications; however, its high reactivity is a limiting factor for its usage. Powder metallurgy is one of the promising methods for the enhancement of material mechanical properties and, due to the introduced plastic deformation, can also have a positive influence on corrosion resistance. Pure magnesium samples were prepared via powder metallurgy. Compacting pressures from 100 MPa to 500 MPa were used for samples' preparation at room temperature and elevated temperatures. The microstructure of the obtained compacts was analyzed in terms of microscopy. The three-point bending test and microhardness testing were adopted to define the compacts' mechanical properties, discussing the results with respect to fractographic analysis. Electrochemical corrosion properties analyzed with electrochemical impedance spectroscopy carried out in HBSS (Hank's Balanced Salt Solution) and enriched HBSS were correlated with the metallographic analysis of the corrosion process. Cold compacted materials were very brittle with low strength (up to 50 MPa) and microhardness (up to 50 HV (load: 0.025 kg)) and degraded rapidly in both solutions. Hot pressed materials yielded much higher strength (up to 250 MPa) and microhardness (up to 65 HV (load: 0.025 kg)), and the electrochemical characteristics were significantly better when compared to the cold compacted samples. Temperatures of 300 • C and 400 • C and high compacting pressures from 300 MPa to 500 MPa had a positive influence on material bonding, mechanical and electrochemical properties. A compacting temperature of 500 • C had a detrimental effect on material compaction when using pressure above 200 MPa.

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Section: Introductionmentioning

confidence: 99%

Characterization of Powder Metallurgy Processed Pure Magnesium Materials for Biomedical Applications

Zapletal

Březina

Krystýnová

et al. 2017

Metals

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“…Except alloying treatment, thermomechanical processes are also an important method to improve the mechanical properties and corrosion resistance of magnesium alloys. Nayak et al [16] found that Grain size got refined significantly with increasing amount of deformation. The Mg-3Zn (wt %) experiences a marked improvement in hardness, yield strength, ultimate tensile strength, strain and toughness with finer grain size through hot-rolled.…”

Section: Introductionmentioning

confidence: 99%

A Potential Biodegradable Mg-Y-Ag Implant with Strengthened Antimicrobial Properties in Orthopedic Applications

Dai

Liu

Tang

et al. 2018

Metals

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In order to design a potential biodegradable implant, which combines with fine mechanical and antimicrobial properties, Mg-4Y-1Ag (mass fraction, %) alloys were produced by permanent mold casting and then hot extrusion. The microstructure, mechanical behavior, anti-corrosion behavior, and antimicrobial properties of the experimental alloys were comprehensively investigated. The results showed that α-Mg, Mg24Y5 (ε), and AgMg4 phases existed in the Mg-4Y-1Ag. The grain size of Mg-4Y-1Ag was greatly refined through hot-extrusion. The as-extruded Mg-4Y-1Ag alloy exhibit an ultimate tensile strength of 202.7 MPa with a good elongation of 33.6%. The compressive strength of as-extruded Mg-4Y-1Ag was 385 MPa, and the strength remained 183 MPa after immersing in PBS solution for four weeks. The as-extruded alloy had better corrosion resistance than as-cast alloy and as-extruded pure magnesium in PBS solution, for the reason of refined grain and the formation of Y2O3 film on the surface of Mg-4Y-1Ag alloy. Furthermore, the as-extruded Mg-4Y-1Ag alloys were superior to Ti6Al4V (TC4) and as-extruded pure magnesium in antimicrobial property for released Ag+ ion. Obvious inhibition halo was observed in the LB agar plate adding with as-extruded Mg-4Y-1Ag alloys. Also as-extruded Mg-4Y-1Ag alloys showed no cytotoxicity by co-culturing with L929 using the MTT method.

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“…Advancement in our knowledge of the mechanics of cells and tissues has led to rapid strides in the area of biomimetics. Implants and artificial organs that mimic the structure and mechanical properties of biological components and systems are being developed for superior functionality . Knowledge of the mechanics of cells and tissues is extremely important in restorative and regenerative medicine .…”

Section: Introductionmentioning

confidence: 99%

The Role of Nanomechanics in Healthcare

Nautiyal

Alam

Balani

et al. 2017

Adv Healthcare Materials

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Nanomechanics has played a vital role in pushing our capability to detect, probe, and manipulate the biological species, such as proteins, cells, and tissues, paving way to a deeper knowledge and superior strategies for healthcare. Nanomechanical characterization techniques, such as atomic force microscopy, nanoindentation, nanotribology, optical tweezers, and other hybrid techniques have been utilized to understand the mechanics and kinetics of biospecies. Investigation of the mechanics of cells and tissues has provided critical information about mechanical characteristics of host body environments. This information has been utilized for developing biomimetic materials and structures for tissue engineering and artificial implants. This review summarizes nanomechanical characterization techniques and their potential applications in healthcare research. The principles and examples of label-free detection of cancers and myocardial infarction by nanomechanical cantilevers are discussed. The vital importance of nanomechanics in regenerative medicine is highlighted from the perspective of material selection and design for developing biocompatible scaffolds. This review interconnects the advancements made in fundamental materials science research and biomedical technology, and therefore provides scientific insight that is of common interest to the researchers working in different disciplines of healthcare science and technology.

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Strengthening of Mg based alloy through grain refinement for orthopaedic application

Cited by 94 publications

References 46 publications

Characterization of Powder Metallurgy Processed Pure Magnesium Materials for Biomedical Applications

Characterization of Powder Metallurgy Processed Pure Magnesium Materials for Biomedical Applications

A Potential Biodegradable Mg-Y-Ag Implant with Strengthened Antimicrobial Properties in Orthopedic Applications

The Role of Nanomechanics in Healthcare

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