Streptococcus pneumoniae as an agent of urinary tract infections – a laboratory experience from 2010 to 2014 and further characterization of strains

Burckhardt, Irene; Panitz, Jessica; Linden, Mark van der; Zimmermann, Stefan

doi:10.1016/j.diagmicrobio.2016.06.009

Cited by 7 publications

(6 citation statements)

References 13 publications

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“…There are few case reports in the literature on UTIs caused by Haemophilus spp., M. catarrhalis, and S. pneumoniae. 6,7 To the best of our knowledge, this may be the first report investigating UTI caused by all three major bacterial pathogens of the respiratory tract. Although UTI due to these bacteria were rare, up to 0.04% of urine cultures, they could be pathogenic.…”

Section: Discussionmentioning

confidence: 88%

“…[6][7][8] A common feature of patients described in those reports in both adults and children was an underlying urinary tract abnormality, such as cystic-dysplastic kidney and chronic kidney disease. [6][7][8] Although we did not have UTIs due to M. catarrhalis, case reports of this were very limited as well. 9 In our cases, 60% had received vesicostomy, which may be a remarkable feature.…”

Section: Discussionmentioning

confidence: 95%

“…There are several reports about UTIs from S. pneumoniae and Haemophilus spp. on a case‐report basis 6–8 . A common feature of patients described in those reports in both adults and children was an underlying urinary tract abnormality, such as cystic‐dysplastic kidney and chronic kidney disease 6–8 .…”

Section: Discussionmentioning

confidence: 99%

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Urinary tract infection caused by bacterial pathogens of the respiratory tract in children

Takahashi

Funaki

Ishiguro

et al. 2022

Pediatrics International

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Urinary tract infection (UTI) caused by bacterial pathogens of the respiratory tract such as Streptococcus pneumoniae, Haemophilus in uenzae, and Moraxella catarrhalis is rare and little is known about their characteristics and potential host risk factors. We conducted a retrospective descriptive study on pediatric UTI due to S. pneumoniae, Haemophilus spp., or M. catarrhalis at a tertiary-care pediatric hospital. Pediatric patients with diagnosed UTI between 2002 and 2020 were included. Patient demographics, laboratory data, and microbiological ndings were extracted from their electronic medical records and the infectious disease surveillance system. Among 46,332 urine samples, 76 bacteriuria (0.16%) and 22 UTI (0.05%) events due to the targeted species were identi ed (S. pneumoniae [n=7] and Haemophilus spp. [n=15]). Of the patients, 17 (85%) had underlying urinary tract abnormalities and 13 (60%) had vesicocutaneous stula. All the UTI episodes caused by S. pneumoniae and Haemophilus spp. occurred after cystostomy. All the patients had satisfactory clinical outcomes.Conclusion: Although S. pneumoniae and Haemophilus spp. are rare causes of UTI in children, they could be the true causative bacteria of UTI even when detected in urine specimens, particularly in the patients with urinary tract abnormalities and vesicocutaneous stula. What Is KnownStreptococcus pneumoniae, Haemophilus in uenzae, and Moraxella catarrhalis are uncommon causes of UTI.Malformations of the urinary tract is risk factors of complex UTI. What is newAlthough S. pneumoniae and Haemophilus spp. are rare causes of UTI in children, they could be the true causative bacteria of UTI Patients with vesicocutaneous stula could be its risk factor.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 95%

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Urinary tract infection caused by bacterial pathogens of the respiratory tract in children

Takahashi

Funaki

Ishiguro

et al. 2022

Pediatrics International

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“…Among survivors, AKI can progress to chronic kidney disease as nephron loss leads to glomerular hypertrophy in the remaining nephrons [ 46 , 223 ]. While Spn is not considered a typical agent of urinary tract infections (UTIs), it has been reported that children with chronic kidney disease have had urinary tract abnormalities associated with Spn infection and clinical UTI symptoms consistent with cystitis [ 224 , 225 ]. Additionally, even in the absence of other disorders, Spn can be the causative agent of UTI, but due to the rarity of these causes more data is needed to evaluate the involvement of the pneumococci in the epidemiology and pathogenesis of UTIs [ 226 ].…”

Section: Organ Damage Occurs During Acute Infection With Lasting Cons...mentioning

confidence: 99%

Acute organ injury and long-term sequelae of severe pneumococcal infections

et al. 2023

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Streptococcus pneumoniae (Spn) is a major public health problem, as it is a main cause of otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis. Acute episodes of pneumococcal disease have been demonstrated to cause organ damage with lingering negative consequences. Cytotoxic products released by the bacterium, biomechanical and physiological stress resulting from infection, and the corresponding inflammatory response together contribute to organ damage accrued during infection. The collective result of this damage can be acutely life-threatening, but among survivors, it also contributes to the long-lasting sequelae of pneumococcal disease. These include the development of new morbidities or exacerbation of pre-existing conditions such as COPD, heart disease, and neurological impairments. Currently, pneumonia is ranked as the 9th leading cause of death, but this estimate only considers short-term mortality and likely underestimates the true long-term impact of disease. Herein, we review the data that indicates damage incurred during acute pneumococcal infection can result in long-term sequelae which reduces quality of life and life expectancy among pneumococcal disease survivors.

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“…Hastanın yaşına bağlı olarak, özellikle 2 yaşından küçük çocuklarda klinik belirtiler daha az tipik olabilir. Genellikle piyüri mevcuttur (2) . Buna karşılık asemptomatik bakteriüri (ABÜ), klinik bulgular olmaksızın, idrarda ''önemli'' sayıda bakteri bulunması (yetişkinlerde >10 5 CFU/mL, çocuklarda >10 4 CFU/mL) durumudur (10) .…”

Section: İye Bakteriüri (Yetişkinlerde >10unclassified

İdrar Yolu Enfeksi̇yonu Etkeni̇ Olarak Streptococcus Pneumoniae

GÜNBEY,

ALICI

2023

ANKEM Dergisi

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Streptococcus pneumoniae, esas olarak orta kulak iltihabına, toplum kökenli pnömoniye hatta bazen bakteriyemiye neden olan Gram pozitif bir koktur. Genellikle üriner sistem enfeksiyonu etkeni olarak kabul edilmez. Dizüri şikayetiyle başvuran 58 yaşındaki erkek hastanın tekrarlanan idrar kültürlerinden Streptococcus pneumoniae izole edilmiştir. Hastada başka enfeksiyon belirtisi bulunmamıştır. İdrar analizlerinde hematüri tespit edilmiştir. Hasta parenteral seftriakson 500 mg 2×1 ile tedavi edilmiştir. Uzun süredir şikayetlerinin olması nedeniyle ileri tetkikler yapıldığında mesane kanseri tanısı konmuştur. İdrarda Streptococcus pneumoniae’nın izole edilmesi idrar yolu enfeksiyonunun nadir bir etkeni olarak kabul edilmeli, üriner sistem anomalisine sebep olacak nedenler araştırılmalıdır.

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Streptococcus pneumoniae as an agent of urinary tract infections – a laboratory experience from 2010 to 2014 and further characterization of strains

Cited by 7 publications

References 13 publications

Urinary tract infection caused by bacterial pathogens of the respiratory tract in children

Urinary tract infection caused by bacterial pathogens of the respiratory tract in children

Acute organ injury and long-term sequelae of severe pneumococcal infections

İdrar Yolu Enfeksi̇yonu Etkeni̇ Olarak Streptococcus Pneumoniae

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