Streptomyces polaris sp. nov. and Streptomyces septentrionalis sp. nov., isolated from frozen soil

Kamjam, Manita; Nopnakorn, Potjanicha; Zhang, Li; Peng, Fang; Deng, Zixin; Hong, Kui

doi:10.1007/s10482-018-1166-x

Cited by 11 publications

(8 citation statements)

References 50 publications

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“…In this experiment, we report the optimum pH for maximum growth is pH 7, and the lowest growth was observed in pH 2. This is very similar to the study by Streptomyces polaris sp by Kamjam et al, (2019).…”

Section: Discussionsupporting

confidence: 92%

“…In this way, responses to environmental signals are transmitted through global transcription factors that mediate environmental signals like carbon (CreA) (Janus et al 2008), nitrogen (AreA) (Tudzynski et al 1999), and pH (PacC) (Tilburn et al 1995), translating environmental cues into Secondary Metabolites and concomitant physiological responses. The enhancement or inhibition of the secondary metabolite is in uenced by a change in pH and can also affect the growth of microorganisms (Kamjam et al 2019). In this experiment, we report the optimum pH for maximum growth is pH 7, and the lowest growth was observed in pH 2.…”

Section: Discussionmentioning

confidence: 65%

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Extraction and Characterization of Antibiotic Compounds produced by Streptomyces spp. VITGV01 against Selected Human Pathogens

Veilumuthu

Siva

Christopher

2021

Preprint

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Streptomyces are well known to produce a large number of diverse antibiotic compounds. New environments are being explored and some new Streptomyces strains have been discovered; the potential of the plant endophytic environments has been highly explored during the last decade. In the present study, an endophytic actinomycete, VITGV01, was isolated from a farm tomato plant collected from an agricultural field. These actinomycetes are cultured in ISP2 medium supplemented with nystatin (15µg/ml) and nalidixic acid (50µg/ml). Based on the 16S rRNA analysis and physiological tests, this isolate was found to be a member of the known genus Streptomyces spp. and suggesting that it might be a new spp. The isolated strain showed morphological and chemical characteristics of the genus Streptomyces. The strain VITGV01 produced different antibiotics on different media such as yeast extract, malt extract, glucose medium, which were active against some Gram-positive and negative bacteria [Bacillus subtilis (MTCC2756), Staphylococcus aureus (MTCC737), Escherichia coli – (MTCC1687), and Klebsiella pneumoniae (MTCC109)]. The primary and secondary screening was performed against these human pathogens. Maximum zone of inhibition was observed against K. pneumoniae (22 mm) and minimal zone of inhibition against B. subtilis (8 mm). Maximum biomass production was recorded in media containing 1% sucrose and 1% yeast extract cultured at pH 7.0 for 7 days at 30◦C. FTIR analysis revealed amine, alkane (C = C) of the aromatic ring, secondary alcohol, and alkyl halide groups. The GC–MS data showed twenty compounds, of which fifteen are antimicrobial compounds.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 65%

Extraction and Characterization of Antibiotic Compounds produced by Streptomyces spp. VITGV01 against Selected Human Pathogens

Veilumuthu

Siva

Christopher

2021

Preprint

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“…possess high adaptive capability for surviving in many extreme environmental conditions and their incidence had been documented in diverse extreme habitats including frozen soils, deserts, oceans, Arctic and Antarctic regions ( Maldonado et al, 2008 ; Le Roes-Hill et al, 2009 ; Malviya et al, 2009 ; Okoro et al, 2009 ; Ramesh and Mathivanan, 2009 ; Verma et al, 2009 ; Ivanova et al, 2010 ; Zothanpuia et al, 2018 ). Studies in frozen soils, Arctic and Antarctic regions had revealed a great diversity of cultivable Streptomyces species ( Le Roes-Hill et al, 2009 ; Ivanova et al, 2010 ; Li et al, 2011 ; Zhang et al, 2016b ; Kamjam et al, 2019 ), while in marine and deserts, Streptomyces spp. had been reported as one of the dominant culturable genera ( Okoro et al, 2009 ; Prieto-Davo et al, 2016 ).…”

Section: Discussionmentioning

confidence: 99%

Phylogenetic and Physiological Diversity of Cultivable Actinomycetes Isolated From Alpine Habitats on the Qinghai-Tibetan Plateau

Zhang

Jiang

et al. 2020

Front. Microbiol.

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Actinomycetes in extreme alpine habitat have attracted much attention due to their unique physiological activities and functions. However, little is known about their ecological distribution and diversity. Here, we explored the phylogenetic relationship and physiological heterogeneity of cultivable actinomycetes from near-root soils of different plant communities in the Laohu Ditch (2200 – 4200 m) and Gaize County area (5018 – 5130 m) on the Qinghai-Tibetan Plateau. A total of 128 actinomycete isolates were obtained, 16S rDNA-sequenced and examined for antimicrobial activities and organic acid, H 2 S, diffusible pigments, various extracellular enzymes production. Seventy three isolates of the total seventy eight isolates from the Laohu Ditch, frequently isolated from 2200 to 4200 m, were closely related to Streptomyces spp. according to the 16S rDNA sequencing, while four isolates within the genus Nocardia spp. were found at 2200, 2800, and 3800 m. In addition, one potential novel isolate with 92% sequence similarity to its nearest match Micromonospora saelicesensis from the GenBank database, was obtained at 2200 m. From the Gaize County area, fifty Streptomyces isolates varied in diversity at different sites from 5018 to 5130 m. The investigation of phenotypic properties of 128 isolates showed that 94.5, 78.9, 68, 64.8, 53, 51.6, 50, 36.7, 31.2, and 22.7% of the total isolates produced catalase, lipase 2, urease, protease, H 2 S, lipase 3, amylase, lipase 1, diffusible pigment and organic acid, respectively. The antimicrobial assays of the total isolates revealed that 5, 28, 19, and 2 isolates from Streptomyces spp. exhibited antimicrobial activity against Escherichia coli , Staphylococcus aureus , Candida albicans , and Pseudomonas aeruginosa , respectively. This study intends to bring helpful insights in the exploitation and utilization of alpine actinomycetes for novel bioactive compounds discovery.

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“…Extremely low cold or cryoenvironment is an inexhaustible microbial habitat which has been emphasised by several studies in recent years [25, 26]. Because of significant climatic variables in extreme cold habitats, microbes inhabiting there can adapt to harsh conditions which can, in turn, produce novel compounds that are valuable for biotechnology applications [27].…”

Section: Extremely Low Cold or Cryoenvironmentmentioning

confidence: 99%

“…from the Antarctic ecosystem and other distinct studies requires to be investigated in such environmental sources [33, 34]. Likewise, recently published papers describe novel Streptomyces isolated from Arctic glacier [25, 26]. But, till date, no studies described yet concerning novel Streptomyces spp.…”

Section: Isolation Of Streptomyces From Cryoenvironmentsmentioning

confidence: 99%

Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads?

Sivalingam

Hong

Poté

et al. 2019

International Journal of Microbiology

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125

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Antimicrobial resistance (AR) is recognized as one of the greatest threats to public health and in global concern. Consequently, the increased morbidity and mortality, which are associated with multidrug resistance bacteria, urgently require the discovery of novel and more efficient drugs. Conversely, cancer is a growing complex human disease that demands new drugs with no or fewer side effects. Most of the drugs currently used in the health care systems were of Streptomyces origin or their synthetic forms. Natural product researches from Streptomyces have been genuinely spectacular over the recent years from extreme environments. It is because of technical advances in isolation, fermentation, spectroscopy, and genomic studies which led to the efficient recovering of Streptomyces and their new chemical compounds with distinct activities. Expanding the use of the last line of antibiotics and demand for new drugs will continue to play an essential role for the potent Streptomyces from previously unexplored environmental sources. In this context, deep-sea, desert, cryo, and volcanic environments have proven to be a unique habitat of more extreme, and of their adaptation to extreme living, environments attribute to novel antibiotics. Extreme Streptomyces have been an excellent source of a new class of compounds which include alkaloids, angucycline, macrolide, and peptides. This review covers novel drug leads with antibacterial and cytotoxic activities isolated from deep-sea, desert, cryo, and volcanic environment Streptomyces from 2009 to 2019. The structure and chemical classes of the compounds, their relevant bioactivities, and the sources of organisms are presented.

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Streptomyces polaris sp. nov. and Streptomyces septentrionalis sp. nov., isolated from frozen soil

Cited by 11 publications

References 50 publications

Extraction and Characterization of Antibiotic Compounds produced by Streptomyces spp. VITGV01 against Selected Human Pathogens

Extraction and Characterization of Antibiotic Compounds produced by Streptomyces spp. VITGV01 against Selected Human Pathogens

Phylogenetic and Physiological Diversity of Cultivable Actinomycetes Isolated From Alpine Habitats on the Qinghai-Tibetan Plateau

Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads?

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