Streptozotosin ile Deneysel Diyabet Oluşturulan Ratlarda Diyetteki Borun Hiperglisemik Etkisi

Abstract

In this study, the effect of boric acid (BA) on blood sugar, some vitamins and minerals in rats administered Streptozotocin (STZ) was investigated. In the study, 48 male Wistar albino rats (200-220 g) were divided into 6 groups, No special treatment was administered to Group1, experimental diabetes was induced by administering STZ (45 mg/kg) through intraperitoneal (IP) injection to other groups. Group2 diabetes group, Group3, (6U/kg insulin). Group4, 250; group5 500; and group6 1000 ppm BA mixed with their feed. Blood glucose levels of all groups were quantified from blood taken from the tail vein every week. End in the study, the rats were sacrificed and their blood was taken. The serum levels of vitamins A, E, and some minerals were studied. When compared with other groups, blood glucose levels of groups 4, 5 and 6 were found to be increased (p