Aim of the Work: This study aimed to evaluate the stress distribution in and around one-piece narrow diameter implants, placed in tilted position, with different degrees of angles retaining mandibular overdenture. Materials and methods: Five finite element models (ABAQUS 13), were created to simulate five proposed groups for this study. Each model composed of the anterior region of edentulous mandible, in which 2 implants were virtually placed on the canine area retaining mandibular overdenture. Vertical, horizontal and oblique loads (35 N), were applied respectively, bilaterally on the both dental implants at the same time, through the overdenture. The maximum stress values (MSV) transmitted to the dental implants and peri-implant bone were analyzed by using finite element analysis (FEA) and compared with the yield strength values of the dental implant, cortical bone and cancellous bone. Results and conclusions: 1.The recordings of MSV at the dental implants and the cortical bone with all of the different proposed groups and loading conditions, were below their yield strength values. While the MSVs at the cancellous bone, exceeded its yield strength value, specially with the vertical load condition applied on the dental implants placed in a tilted position. 2. The MSVs taken from the dental implants and its surrounding bone, that placed vertically were less than the MSVs in and around the dental implants placed in the tilted position. 3. For the dental implants and its surrounding bone, placed with an equal degree of a tilted position, the MSVs decreased when the angle of placement increased.