Stress-associated changes in the steady-state expression of latent Epstein–Barr virus: Implications for chronic fatigue syndrome and cancer

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph

“…Epstein Barr virus, which is normally well controlled by host immune responses but can be sub-clinically reactivated by a variety of stress signals, might trigger B-cell activation. 3 Such Epstein Barr virus reactivation is reflected by aberrant Epstein Barr virus seroreactivity. This process might become functional in the background of "minor" genetic defects that increase the chance of erroneous events over time.…”

Frequency of Chronic Fatigue Syndrome Symptoms Among Nurses

“…Ancak Epstein-Barr, Herpes virüsün kronik yorgunluk sendromu semptomlarını tetiklediğine dair bilgiler vardır (10,11). İncline, Nevada, Punta Gorda ve diğer yerlerde görülen salgınlar, kronik yorgunluk sendromunun bulaşıcı bir hastalık olduğunu düşündürmüşse de; kişiden kişiye bulaşma tespit edilememiş ve bu çalışmalar içinde değerlendirilen hastalar kronik yorgunluk sendromu kriterlerini taşımamışlardır.…”

Pediatric Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

“…For example, Miike and colleagues [38] found that cortisol secretion was reduced in a pediatric ME/CFS population in comparison to controls. In addition, prior adverse events can "prime" inflammatory responses, promoting excessive cytokine production in response to subsequent stressors [39]. Thus, prior life adversity may produce stable alterations in processes that regulate the inflammatory response to subsequent stress [40].…”