Stress distribution within the left ventricular wall approximated as a thick ellipsoidal shell

Wong, Alan Y.K.; Rautaharju, Pentti M.

doi:10.1016/0002-8703(68)90325-6

Cited by 203 publications

(80 citation statements)

References 13 publications

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“…Pathoanatomical studies (21,22) support the results of our study. Strain is closely related to the load to which the muscle is exposed during contraction.…”

Section: Longitudinal and Circumferential Strainsupporting

confidence: 90%

Strain‐encoded MRI to evaluate normal left ventricular function and timing of contraction at 3.0 Tesla

Hamdan

Thouet

Kelle

et al. 2009

Magnetic Resonance Imaging

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Purpose:To define the reproducibility of strain-encoded (SENC) magnetic resonance imaging (MRI) for assessment of regional left ventricular myocardial strain and timing of contraction in a 3T MRI system. Materials and Methods:The study population consisted of 16 healthy subjects. SENC measurements were performed in three short-axis (SA) slices (apical, mid, and basal) and three long-axis (LA) views (two-, three-, and four-chamber) for assessment of maximal transmural systolic strain and time to peak strain. To assess the interobserver and interstudy reproducibility, analysis of SENC MRI was performed by two independent observers who were blinded to each other's results and four studies were repeated on a different day.Results: Maximal longitudinal strain was highest at the apex, as was maximal circumferential strain. Peak longitudinal strain occurred earliest at the base, as did peak circumferential strain. Interclass correlation coefficient between observers and repeated studies ranged from 0.92 to 0.98 (P Ͻ 0.001 for all). Conclusion:The present study demonstrates the ability of SENC MRI to define regional left ventricular strain and the time sequence of regional strain. SENC MRI may represent a highly objective method for quantifying regional left ventricular function.

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“…Pathoanatomical studies (21,22) support the results of our study. Strain is closely related to the load to which the muscle is exposed during contraction.…”

Section: Longitudinal and Circumferential Strainsupporting

confidence: 90%

Strain‐encoded MRI to evaluate normal left ventricular function and timing of contraction at 3.0 Tesla

Hamdan

Thouet

Kelle

et al. 2009

Magnetic Resonance Imaging

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“…Thus, with a constant contractility assumed, an increase in stress must lead to a decrease in strain. Stress, in turn, is determined by local radii of curvature (21,29), which for radial and meridional stress can be approximated by endsystolic diameters (8). As a confirmation, Bogaert et al (3) used magnetic resonance imaging to show that strains decrease in the remote regions after myocardial infarct and that this decrease is associated with increased circumferential and longitudinal radii of curvature (3).…”

Section: Discussionmentioning

confidence: 99%

Speckle-tracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of myocardial infarction

Popović

Benejam

Bian

et al. 2007

American Journal of Physiology-Heart and Circulatory Physiology

110

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MS. Speckletracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of myocardial infarction. Am J Physiol Heart Circ Physiol 292: H2809 -H2816, 2007. First published February 2, 2007; doi:10.1152/ajpheart.01176.2006.-Speckle-tracking echocardiography (STE) uses a two-dimensional echocardiographic image to estimate two orthogonal strain components. The aim of this study was to assess sensitivity of circumferential (Scirc) and radial (Srad) strains to infarct-induced left ventricular (LV) remodeling and scarring of the LV in a rat. To assess the relationship among Scirc, Srad, and scar size, two-dimensional echocardiographic LV short-axis images (12 MHz transducer, Vivid 7 echo machine) were collected in 34 Lewis rats 4 to 10 wk after ligation of the left anterior descending artery. Percent segmental fibrosis was assessed from histological LV cross sections stained by Masson trichrome. Ten normal rats served as echocardiographic controls. Scirc and Srad were assessed by STE. Histological data showed consistent scarring of anterior and lateral segments with variable extension to posterior and inferior segments. Both Scirc and Srad significantly decreased after myocardial infarction (P Ͻ 0.0001 for both). As anticipated, Scirc and Srad were lowest in the infarcted segments. Multiple linear regression showed that segmental S circ were similarly dependent on segmental fibrosis and end-systolic diameter (P Ͻ 0.0001 for both), whereas segmental S rad measurements were more dependent on end-systolic diameter (P Ͻ 0.0001) than on percent fibrosis (P Ͻ 0.002). STE correctly identifies segmental LV dysfunction induced by scarring that follows myocardial infarction in rats.infarction; collagen; contractility RECENT ADVANCES in noninvasive imaging of the left ventricle (LV) have enabled the quantification of regional function with an accuracy and simplicity that were not available previously. One of these newer methods is speckle-tracking echocardiography (STE). STE uses a standard two-dimensional echocardiographic image to estimate two orthogonal strain components (25). This method has a potential to revolutionize noninvasive assessment of regional ventricular (and possibly atrial) function (25). Although similar data can be extracted by Doppler tissue echocardiography (2), the value of this method is the freedom of the insonation angle and an ability to adopt a local coordinate system for strain measurement.Although STE was recently validated in a variety of settings (1,5,10,17, 22), the relationship of strain to underlying muscle histology is uncertain. It is unknown as to what measure a decreased strain represents muscle loss, presence of ischemia, or a simple contractility decrease. Finally, the applicability of this method to small-animal echocardiography is unknown.The aim of this study was to assess sensitivity of circumferential (S circ ) and radial (S rad ) midwall strain components to LV remodeling and scarring induced by the myocardial infarction (MI...

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“…In one it was realized that ventricular state variables reflect a corresponding state of the ventricular myocardium in its interaction with the complex and variable geometry of the ventricle. A number of papers have been published (6,10,17,70,94,111) describing models of ventricular pressure generation based on a detailed inventory of cardiac muscle mechanics and ventricular anatomy. Global and measurable ventricular phenomena could thus be described; but no useful new definitions of ventricular performance arose from them.…”

Section: Introductionmentioning

confidence: 99%

The step response of left ventricular pressure to ejection flow: A system oriented approach

Boom

Wijkstra

1992

Ann Biomed Eng

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Stress distribution within the left ventricular wall approximated as a thick ellipsoidal shell

Cited by 203 publications

References 13 publications

Strain‐encoded MRI to evaluate normal left ventricular function and timing of contraction at 3.0 Tesla

Strain‐encoded MRI to evaluate normal left ventricular function and timing of contraction at 3.0 Tesla

Speckle-tracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of myocardial infarction

The step response of left ventricular pressure to ejection flow: A system oriented approach

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