Stress echocardiography for selecting potential responders to cardiac resynchronisation therapy

Moonen, Marie; O’Connor, Kim; Magné, Julien; Lancellotti, Patrizio; Piérard, Luc

doi:10.1136/hrt.2010.199828

Cited by 15 publications

(5 citation statements)

References 44 publications

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“…It is important to decide which gated images to use to derive dyssynchrony indices (stress versus rest), at least in patients with normal MPI. There has been increasing interest in assessing mechanical dyssynchrony from stress echocardiography with promising results [19,20]. Recent studies have shown that mechanical dyssynchrony indices derived from low-dose dobutamine stress echocardiogram [21] and from bicycle exercise echocardiogram [22] were better predictors of response to CRT than resting echocardiography.…”

Section: Discussionmentioning

confidence: 99%

Effect of stress testing on left ventricular mechanical synchrony by phase analysis of gated positron emission tomography in patients with normal myocardial perfusion

AlJaroudi

Alraies

DiFilippo

et al. 2012

Eur J Nucl Med Mol Imaging

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Section: Discussionmentioning

confidence: 99%

Effect of stress testing on left ventricular mechanical synchrony by phase analysis of gated positron emission tomography in patients with normal myocardial perfusion

AlJaroudi

Alraies

DiFilippo

et al. 2012

Eur J Nucl Med Mol Imaging

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“…40 The presence of viable myocardium predicts LV reverse remodelling and a better outcome after revascularization, beta-blocker therapy and cardiac resynchronization therapy CRT. 44 LV reverse remodelling and reduced mitral apparatus deformation after CRT are associated with a reduction in both resting and exercise-induced MR and an improvement in cardiopulmonary performance. 45 Moreover, SMR decreases more significantly in patients with viability in the region of the pacing lead after CRT.…”

Section: Role Of Esementioning

confidence: 97%

Exercise Testing in Mitral Regurgitation

Marchetta

Sugimoto

et al. 2017

Progress in Cardiovascular Diseases

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Mitral regurgitation (MR) is the second most common valvular heart disease referred for corrective surgery. Diagnostic and management dilemmas are not uncommon when dealing with MR patients. Exercise testing plays an important role in sorting out some of these clinical challenges. In primary asymptomatic MR, exercise testing allows symptom assessment, confident link of symptoms to valve disease severity, safe deferral of surgery for the next 1-year in patients with preserved exercise capacity, insights into the mechanism of exercise-induced dyspnea and helps in individual risk stratification. Moreover, exercise testing in the form of exercise stress echocardiography is also useful in the evaluation of patients with secondary ischemic MR for risk stratification as well as for the detection of patients with moderate ischemic MR in whom mitral valve repair at the time of surgical revascularization may add benefit.

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“…The proposal that exercise worsens dyssynchrony, which consequently increases MR, warrants further study and might indicate the need for CRT in affected patients. 58,59 Percutaneous mitral valve intervention In the past 5 years, the introduction of percutaneous mitral valve intervention (PMVI) techniques has opened new frontiers in MR therapy, by eliminating the need for thoracotomy and extracorporeal circulation. 60 PMVI techniques can correct MR by means of direct or indi rect reduction of mitral annular dilatation, or through treatment of the primary or secondary abnormalities of the mitral apparatus.…”

Section: Cardiac Resynchronization Therapymentioning

confidence: 99%

Therapeutic decision-making for patients with fluctuating mitral regurgitation

2015

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| Mitral regurgitation (MR) is a common, progressive, and difficult-to-manage disease. MR is dynamic in nature, with physiological fluctuations occurring in response to various stimuli such as exercise and ischaemia, which can precipitate the development of symptoms and subsequent cardiac events. In both chronic primary and secondary MR, the dynamic behaviour of MR can be reliably examined during stress echocardiography. Dynamic fluctuation of MR can also have prognostic value; patients with a marked increase in regurgitant volume or who exhibit increased systolic pulmonary artery pressure during exercise have lower symptom-free survival than those who do not experience significant changes in MR and systolic pulmonary artery pressure during exercise. Identifying patients who have dynamic MR, and understanding the mechanisms underlying the condition, can potentially influence revascularization strategies (such as the surgical restoration of coronary blood flow) and interventional treatment (including cardiac resynchronization therapy and new approaches targeted to the mitral valve).

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Stress echocardiography for selecting potential responders to cardiac resynchronisation therapy

Cited by 15 publications

References 44 publications

Effect of stress testing on left ventricular mechanical synchrony by phase analysis of gated positron emission tomography in patients with normal myocardial perfusion

Effect of stress testing on left ventricular mechanical synchrony by phase analysis of gated positron emission tomography in patients with normal myocardial perfusion

Exercise Testing in Mitral Regurgitation

Therapeutic decision-making for patients with fluctuating mitral regurgitation

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