Stress-induced atrial fibrillation

Abstract

Психогенная провокация сердечно-сосудистых заболеваний (ССЗ) стала предметом исследования кардиологов, психиатров, психологов и представителей других специальностей с середины XX века после появления работ W. Cannon [1], впервые описавшего гуморально-гормональные изменения при различных эмоциональных состояниях (страхе, гневе и т.д.), и H. Selye [2], сформулировавшего концепцию «стресса» (стресс-синдрома). Психогенно провоцированные ССЗ возникают в связи как с тяжелым неспецифическим стрессом (катастрофы и катаклизмы), так и с психотравмирующими ситуациями высокой личностной значимости. Последние варьируют от условно-патогенных обстоятельств обыденной жизни до стрессогенных в истинном смысле-смерть супруга или

Effectiveness of Treating Patients with Stable Ischemic Heart Disease and Co-Existent Paroxysmal Atrial Fibrillation with Mebicar

“…The role of the sympathetic and parasympathetic nervous systems in the development of heart arte variability (HRV) was found to be as follows: during an emotional reaction, anger occurs, sympathetic activity and heart rate (HR) increase; however, HRV, that is an indicator of parasympathetic activity, does not change. Due to this, we can conclude, that this is the mechanism of arrhythmogenesis [5]. There are many research works, that proved the excessive production of free radicals and the development of oxidative stress to be the leading mechanisms of initiation and progression of AF [4].…”

“…According to Engel C.L., the cause of sudden cardiac death from psycho-emotional stress can be increased activity of the sympathetic and parasympathetic nervous systems [3,5]. The increase in the sympathetic tone, the decrease in the vagal tone and cardiac anxiety symptoms can be the main provocative factors of AF acting as triggers and modulating ANS [6].…”

Effectiveness of Treatment With Mebicar in Patients With Permanent Atrial Fibrillation

“…Anxiety-depressive symptoms [5], negative emotions [8], and the impact of chronic stress were considered by cardiologists and psychiatrists a long time ago [9]. For many decades, the theory of psychosomatic heart disease has been formed [9]. Clinical trials have been conducted to study the role of depression, anger, anxiety and chronic stress with AF incidents.…”

“…As a rule, stress-induced rhythm disturbance is manifested by tachyarrhythmias characterized by a pathologically rapid rhythm. Conditionally, they can be divided into organic-associated with any pathology of the heart muscle or vessels, most often it is SIHD, myocardial infarction, myocarditis, cardiosclerosis, cardiomyopathies and inorganic (functional) -have no basis for organic lesions, the main causes of their development there are physical and psychological overload, emotional shock, frequent stress situations, intoxication, hypoxia, alcohol, smoking [9].…”

“…The interaction of the cardiovascular and nervous system is a complicated algorithm in a state of rest, and in the period of stress these reactions become even more complex and dynamic. Negative emotions lead to coronary ischemia, platelet activation, changes in hemodynamics and the release of catecholamines in the blood, as well as cause electrical dissociation in the atria and ventricles [9].…”